Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
Location | 4631935..4632616 | Replicon | chromosome |
Accession | NZ_CP049161 | ||
Organism | Pseudomonas aeruginosa strain MS14403 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | WPAWT_RS21380 | Protein ID | WP_015503432.1 |
Coordinates | 4632251..4632616 (-) | Length | 122 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | WPAWT_RS21375 | Protein ID | WP_016561576.1 |
Coordinates | 4631935..4632258 (-) | Length | 108 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
WPAWT_RS21335 | 4627827..4628510 | - | 684 | WP_003120766.1 | TetR/AcrR family transcriptional regulator | - |
WPAWT_RS21340 | 4628598..4629476 | + | 879 | WP_003163191.1 | hypothetical protein | - |
WPAWT_RS21350 | 4630079..4630306 | + | 228 | WP_014603215.1 | hypothetical protein | - |
WPAWT_RS21355 | 4630321..4630863 | - | 543 | WP_019396018.1 | tyrosine-type recombinase/integrase | - |
WPAWT_RS21360 | 4631038..4631313 | - | 276 | WP_004353146.1 | hypothetical protein | - |
WPAWT_RS21365 | 4631313..4631645 | - | 333 | WP_016561578.1 | hypothetical protein | - |
WPAWT_RS21370 | 4631700..4631819 | + | 120 | Protein_4226 | IS5/IS1182 family transposase | - |
WPAWT_RS21375 | 4631935..4632258 | - | 324 | WP_016561576.1 | XRE family transcriptional regulator | Antitoxin |
WPAWT_RS21380 | 4632251..4632616 | - | 366 | WP_015503432.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
WPAWT_RS21385 | 4632880..4633122 | - | 243 | WP_043884955.1 | hypothetical protein | - |
WPAWT_RS21390 | 4633329..4633601 | + | 273 | WP_003085667.1 | hypothetical protein | - |
WPAWT_RS21395 | 4633620..4634045 | - | 426 | WP_003114206.1 | ring-cleaving dioxygenase | - |
WPAWT_RS21400 | 4634146..4635030 | + | 885 | WP_003454589.1 | LysR family transcriptional regulator | - |
WPAWT_RS21405 | 4635003..4635956 | - | 954 | WP_003085661.1 | LysR family transcriptional regulator | - |
WPAWT_RS21410 | 4636177..4636611 | + | 435 | WP_016253806.1 | RidA family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 122 a.a. Molecular weight: 13798.14 Da Isoelectric Point: 4.8219
>T150660 WP_015503432.1 NZ_CP049161:c4632616-4632251 [Pseudomonas aeruginosa]
VAWDIEYTDEFGDWWGSLSEDEQESLAVTVRLLEERGPSLGHPHSSGINGSRPGHMRELRTQHGGRPFRTLYAFDPRRSA
ILPIGGDKTGDDRWYELNVPIADRLHDEHLHQLREEGLIDG
VAWDIEYTDEFGDWWGSLSEDEQESLAVTVRLLEERGPSLGHPHSSGINGSRPGHMRELRTQHGGRPFRTLYAFDPRRSA
ILPIGGDKTGDDRWYELNVPIADRLHDEHLHQLREEGLIDG
Download Length: 366 bp
>T150660 NZ_CP064871:389911-390063 [Xanthomonas oryzae pv. oryzicola]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA
Antitoxin
Download Length: 108 a.a. Molecular weight: 11903.72 Da Isoelectric Point: 5.8900
>AT150660 WP_016561576.1 NZ_CP049161:c4632258-4631935 [Pseudomonas aeruginosa]
MAKKFSDLRAQMSPEAQARVEAKAQELLAEMPLNELRQSRGLSQKMLSEVLQVQQPAIAKMERRTDMYISTLRSHIEAMG
GQLEVIARFPDGAVKISNFADIEEAGA
MAKKFSDLRAQMSPEAQARVEAKAQELLAEMPLNELRQSRGLSQKMLSEVLQVQQPAIAKMERRTDMYISTLRSHIEAMG
GQLEVIARFPDGAVKISNFADIEEAGA
Download Length: 324 bp
>AT150660 NZ_CP064871:390138-390272 [Xanthomonas oryzae pv. oryzicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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