Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 5291936..5292716 Replicon chromosome
Accession NZ_CP049139
Organism Herbaspirillum frisingense strain IAC152

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag G5S34_RS24115 Protein ID WP_182995042.1
Coordinates 5292420..5292716 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag G5S34_RS24110 Protein ID WP_182993298.1
Coordinates 5291936..5292418 (-) Length 161 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5S34_RS24090 5286997..5288568 - 1572 WP_102662647.1 MCP four helix bundle domain-containing protein -
G5S34_RS24095 5288742..5289572 - 831 WP_182993297.1 amidohydrolase family protein -
G5S34_RS24100 5289569..5290810 - 1242 WP_102662645.1 MFS transporter -
G5S34_RS24105 5291187..5291918 + 732 WP_006461190.1 GntR family transcriptional regulator -
G5S34_RS24110 5291936..5292418 - 483 WP_182993298.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
G5S34_RS24115 5292420..5292716 - 297 WP_182995042.1 type II toxin-antitoxin system MqsR family toxin Toxin
G5S34_RS24120 5293160..5293846 + 687 WP_202032464.1 glutathione transferase -
G5S34_RS24125 5293931..5295186 - 1256 Protein_4757 MFS transporter -
G5S34_RS24130 5295649..5296377 + 729 WP_182993299.1 FCD domain-containing protein -
G5S34_RS24135 5296389..5297165 - 777 WP_102662641.1 DeoR/GlpR family DNA-binding transcription regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11177.04 Da        Isoelectric Point: 9.4854

>T150607 WP_182995042.1 NZ_CP049139:c5292716-5292420 [Herbaspirillum frisingense]
MEKHTPHRKLYQIHSLLAQGRIRKTATAILGAAALGMDESEMTTVVAALKSSDFYKSMTSHLDHRIWHDVYCPLTRHGVL
YIKLTVLDDVLIVSFKER

Download         Length: 297 bp

>T150607 NZ_CP064831:c3637046-3636699 [Morganella morganii subsp. morganii]
ATGGCCTATTATGCATTATCGACAGGTGTTATTACCTGTTCACAGGCGGCGGGGCGCTTCAGACGTAATATGCCTCCGGA
AATTCCGGTTATTCTGCCGGGACGTCTTGCTGTTGATGAAAGCGTAAAAGGCAGAGGGATCGGACGGGGTCTGATAAAAG
ATGCCGCACTGCGGGTCTTGCAGGCAGCCGGGATTGTGGGTATCCGCGGTATTGTTGTCCGTGCTCTGTCTGATAATGCC
AGACGTTTTTATGAGCATACCGGTTTTATACCGTCACCGGCTGACCCGATGCTGCTGATGATTACATTACGGGATCTGCA
GCTGGCAACCGGTATCTATTCTGAATAG

Antitoxin


Download         Length: 161 a.a.        Molecular weight: 17782.59 Da        Isoelectric Point: 7.5724

>AT150607 WP_182993298.1 NZ_CP049139:c5292418-5291936 [Herbaspirillum frisingense]
MNCPSCGGAEMVRATRDLPYTYKGETTLIVDVTGDYCPLCGECLPLPAEEERVSFEALAFNKEVNAGLIDPSEIIEAREL
LQLGQREASLLFGGGINAFNRYEAGKIKPPRALVLLLRLLRRHPELLAEVRAGTNDVARPPRILEIREPRVARLTQGRRK

Download         Length: 483 bp

>AT150607 NZ_CP064831:c3637351-3637046 [Morganella morganii subsp. morganii]
ATGACAAAACACACAGATGAGCAGCATCCTGTGTCCGGCGTGAATATCACCCGTTCAACACTGAATTTACGCATCAAACC
GGAAGATAAAATTCTGATTGATCGCGCAGCGCATGCTGCCGGTAAAAACAGAACCGAGTTCGTACTGGAAGCTGCGCGGC
GTGCCGCCGAAGAAACACTGGCAGATTTACGGGTTATTGATGTCAGTACCGATGTCTATCAGCAGTTTATTACCAGACTG
GATATGGCACCACAGTCCGGTGAGGCGCTTCACGGACATTTGTCGTCTGTCACCATAACCGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References