Detailed information of TA system TA150476

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 2057194..2057342
• Replicon: chromosome
• Accession: NZ_CP049091
• Organism: Staphylococcus haemolyticus strain SE3.9

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: RES7_RS10050
• Protein ID: WP_103421963.1
• Coordinates: 2057194..2057289 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2057307..2057342 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RES7_RS10020 (RES7_010005)	2053398..2053814	-	417	WP_011276552.1	DUF1934 family protein	-
RES7_RS10025 (RES7_010010)	2054105..2054200	+	96	WP_107109960.1	type I toxin-antitoxin system Fst family toxin	-
RES7_RS10030 (RES7_010015)	2054630..2054722	-	93	Protein_1965	IS6 family transposase	-
RES7_RS10035 (RES7_010020)	2055172..2055690	-	519	WP_161511582.1	type 1 glutamine amidotransferase domain-containing protein	-
RES7_RS10040 (RES7_010025)	2055778..2056413	-	636	WP_161511581.1	3-hexulose-6-phosphate synthase	-
RES7_RS10045 (RES7_010030)	2056516..2056866	+	351	WP_161511580.1	helix-turn-helix domain-containing protein	-
RES7_RS10050 (RES7_010035)	2057194..2057289	+	96	WP_103421963.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2057307..2057342	+	36	-	-	Antitoxin
RES7_RS10055 (RES7_010040)	2057415..2060036	-	2622	WP_161511579.1	AAA family ATPase	-
RES7_RS10060 (RES7_010045)	2060249..2061019	-	771	WP_213987897.1	ABC transporter permease	-
RES7_RS10065 (RES7_010050)	2061021..2061716	-	696	WP_161517093.1	ATP-binding cassette domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3671.42 Da
• Isoelectric Point: 9.5124

>T150476 WP_103421963.1 NZ_CP049091:2057194-2057289 [Staphylococcus haemolyticus]
MLEIFVHITTTVISGCIIALFTHWLRNRKEK

Nucleotide

• Length: 96 bp

>T150476 NZ_CP064689:c8381849-8381451 [Bradyrhizobium sp. 200]
ATGCTTACCTACATGCTTGACACAAACATCTGCATCTATGTCATGAAGAACTATCCGATCGAGCTGCGTGAAAAGTTCAA
TGCATTGGCCGAGCAACTCTGCATCTCCAGCATCACGCTCGGCGAGTTGCACTATGGCGCAGAAAAGTCTGCACGCCGCG
CCCACAACCTAACGGCAATCGAGCATTTTGTGGCGCGCCTCGATGTGCTGCCCTTTGCTGAGAAGGCGGCTGCGCACTAC
GGTCAGGTCCGAGCGGAACTGGAGCGCGCGGGAACACCCGGTGGTCCGCACGACATGCAAATCGGCGGTCATGCCCGCAG
CGAAGGCTTGATCGTCGTCACCAACAATATGCGCGAGTTCGCCCGTATGCCGGGGGTCAGAGCCGAAAACTGGATCTGA

Antitoxin

Nucleotide

• Length: 36 bp

>AT150476 NZ_CP049091:2057307-2057342 [Staphylococcus haemolyticus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin