150458

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 1698794..1699444 Replicon chromosome
Accession NZ_CP049089
Organism Glaesserella parasuis strain vHPS7

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag G5C67_RS08290 Protein ID WP_062923967.1
Coordinates 1698794..1699132 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag G5C67_RS08295 Protein ID WP_005710405.1
Coordinates 1699136..1699444 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5C67_RS08245 1694409..1694783 + 375 WP_035496549.1 cytochrome B562 -
G5C67_RS08250 1694904..1695828 + 925 Protein_1598 transposase -
G5C67_RS08255 1695783..1696049 + 267 Protein_1599 cation-transporting ATPase PacS -
G5C67_RS08265 1696516..1697955 - 1440 WP_035496906.1 glutamate--tRNA ligase -
G5C67_RS08290 1698794..1699132 + 339 WP_062923967.1 toxin Toxin
G5C67_RS08295 1699136..1699444 + 309 WP_005710405.1 helix-turn-helix domain-containing protein Antitoxin
G5C67_RS08300 1699645..1700805 + 1161 WP_010786053.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
G5C67_RS08305 1700905..1701486 + 582 WP_035496524.1 type IV pilus biogenesis/stability protein PilW -
G5C67_RS08310 1701547..1702482 + 936 WP_005710401.1 KpsF/GutQ family sugar-phosphate isomerase -
G5C67_RS08315 1702482..1702970 + 489 WP_035496521.1 transcription elongation factor GreB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-86)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13244.26 Da        Isoelectric Point: 9.8649

>T150458 WP_062923967.1 NZ_CP049089:1698794-1699132 [Glaesserella parasuis]
MNVAFVELPPFEEYRKKYLDDDTFRLLQNELLKFPDKGELIQGTGGLRKLRIVDIIRQKGKRGGARVIYYYYVQGKQVWL
FHAYNKNQQDDLSNEERVVLANTLSYLKSLVR

Download         Length: 339 bp

>T150458 NZ_CP064682:c3161903-3161607 [Escherichia coli K-12]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11539.61 Da        Isoelectric Point: 10.2919

>AT150458 WP_005710405.1 NZ_CP049089:1699136-1699444 [Glaesserella parasuis]
MGKLFNELMEGMQALELHLQGKITLKTTVVEVPDPIVITPEEVKAIRQKLNLSQAVFARKLHTSVRTYQGWEQGRTKPNP
QAVLLLKMVEKSPKTFEQIASI

Download         Length: 309 bp

>AT150458 NZ_CP064682:c3161605-3161210 [Escherichia coli K-12]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References