Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 823872..824463 Replicon chromosome
Accession NZ_CP049044
Organism Pseudomonas psychrophila strain KM02

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag G5J76_RS03585 Protein ID WP_048352552.1
Coordinates 824185..824463 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag G5J76_RS03580 Protein ID WP_048352553.1
Coordinates 823872..824177 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G5J76_RS03550 819344..820030 + 687 WP_046808830.1 HAD family hydrolase -
G5J76_RS03555 820201..820527 - 327 WP_019828260.1 hypothetical protein -
G5J76_RS03560 821009..822346 - 1338 WP_019828259.1 ammonium transporter -
G5J76_RS03565 822381..822719 - 339 WP_002555808.1 P-II family nitrogen regulator -
G5J76_RS03570 823136..823396 + 261 WP_019828258.1 accessory factor UbiK family protein -
G5J76_RS03575 823442..823870 + 429 WP_019828257.1 VOC family protein -
G5J76_RS03580 823872..824177 - 306 WP_048352553.1 HigA family addiction module antidote protein Antitoxin
G5J76_RS03585 824185..824463 - 279 WP_048352552.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G5J76_RS03590 824639..826132 + 1494 WP_048352551.1 YifB family Mg chelatase-like AAA ATPase -
G5J76_RS03595 826142..827062 - 921 WP_019828228.1 LysR family transcriptional regulator -
G5J76_RS03600 827215..828630 + 1416 WP_037032677.1 NorM family multidrug efflux MATE transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-97)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10426.07 Da        Isoelectric Point: 9.4170

>T150319 WP_048352552.1 NZ_CP049044:c824463-824185 [Pseudomonas psychrophila]
MIINFKCCRTERLFRSGKTRAWSDIINVVERKLTMLDAASVLSDLLSPPGNRLEALGGNRKGQHSIRINAQWRICFIWGA
NGPEAVEIVDYH

Download         Length: 279 bp

>T150319 NZ_CP064674:869047-869460 [Salmonella sp. SJTUF14076]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTGATTTTATTGATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGTCAGGGAGAGATCAAGCTACTCATGGACGGGCGCTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCATCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CAGGCCAACACTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11290.15 Da        Isoelectric Point: 7.2443

>AT150319 WP_048352553.1 NZ_CP049044:c824177-823872 [Pseudomonas psychrophila]
MIKNGMRPVHPGEILKEEYLEPLSLSAAALARALKVSTPTVNDIVLQRRGVSADMALRLAICLETTPEFWLNLQTTYDLR
KAQIERGAAIREQVEPIHHCA

Download         Length: 306 bp

>AT150319 NZ_CP064674:868800-869066 [Salmonella sp. SJTUF14076]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGATGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References