Detailed information of TA system TA150297

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 3855736..3856322
• Replicon: chromosome
• Accession: NZ_CP049017
• Organism: Xanthomonas theicola strain CFBP 4691

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: G4Q83_RS18005
• Protein ID: WP_128421763.1
• Coordinates: 3856041..3856322 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: G4Q83_RS18000
• Protein ID: WP_128421764.1
• Coordinates: 3855736..3856026 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G4Q83_RS17975	3852005..3852112	-	108	Protein_3541	IS630 family transposase	-
G4Q83_RS17980	3852139..3853155	-	1017	WP_185817250.1	IS30 family transposase	-
G4Q83_RS17985	3853419..3854155	-	737	Protein_3543	restriction endonuclease	-
G4Q83_RS17990	3854379..3854822	-	444	WP_128421767.1	hypothetical protein	-
G4Q83_RS17995	3854924..3855586	-	663	WP_128421765.1	hemolysin III family protein	-
G4Q83_RS18000	3855736..3856026	-	291	WP_128421764.1	HigA family addiction module antidote protein	Antitoxin
G4Q83_RS18005	3856041..3856322	-	282	WP_128421763.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
G4Q83_RS18010	3856494..3858989	+	2496	WP_128421762.1	DEAD/DEAH box helicase	-
G4Q83_RS18015	3859516..3860211	+	696	WP_128421766.1	ribonuclease H-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3852139..3881290	29151

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (4-93)

Antitoxin

• Toxin-antitoxin system, antidote protein, HigA (1-94)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10989.55 Da
• Isoelectric Point: 10.6014

>T150297 WP_128421763.1 NZ_CP049017:c3856322-3856041 [Xanthomonas theicola]
VIRNFVDKEAEKIWQRTPSRRWPAEIQAVARRKLRMLNSAATLDDLRVPPANRLEALEGNRKGRYGIRINDQWRVCFQWK
DGDALDVKTVDYH

Nucleotide

• Length: 282 bp

>T150297 NZ_CP064671:896801-897199 [Salmonella sp. SJTUF14152]
ATGCTGAAATTCATGCTTGATACCAATACCTGTATTTTCACCATCAAAAATAAGCCCGAACACATCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCGCCGG
AGCGTAATCTTGCCGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTCTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTGCCGAACTGGCCCGCAAGGGAACACCTGTCGGGCCTTATGACCAGATGATTGCTGGCCATGCCCGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAGTTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10429.08 Da
• Isoelectric Point: 10.5812

>AT150297 WP_128421764.1 NZ_CP049017:c3856026-3855736 [Xanthomonas theicola]
MKTLPNIHPGEVLLEEFLTPLDISQNALARAAGVPPRRINEIVLGKRSVTADTAIRLAAALGTSERFWLGLQADYDLEQA
RRALGAQARKIARIAA

Nucleotide

• Length: 291 bp

>AT150297 NZ_CP064671:896574-896801 [Salmonella sp. SJTUF14152]
ATGCACACAACACTTTTTTTTAGTAACCGGACCCAGGCAGTCAGATTGCCTAAATCGATATCCTTTCCGGATGATGTGAA
ACATGTCGAAATCATTGCGGTTGGTAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGGACAGCTGGTTCGATGGCG
AAGGCGCCAGTACTGATTTTATGAGTACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGATTCTGA