Detailed information of TA system TA150134

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/COG4683-HTH_37
• Location: 6034595..6035281
• Replicon: chromosome
• Accession: NZ_CP048878
• Organism: Spartinivicinus ruber strain S2-4-1H

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: G4Y78_RS27220
• Protein ID: WP_163836090.1
• Coordinates: 6034931..6035281 (-)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: G4Y78_RS27215
• Protein ID: WP_163836089.1
• Coordinates: 6034595..6034915 (-)
• Length: 107 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	pilM / pilJ / pilH / pilG / pilU / pilT	5758046..6217034	458988

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (12-104)

Antitoxin

• Cro/C1-type helix-turn-helix domain (33-84)

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 13591.70 Da
• Isoelectric Point: 7.2784

>T150134 WP_163836090.1 NZ_CP048878:c6035281-6034931 [Spartinivicinus ruber]
MWKVVTVDEFDQWFLGLNEAEQVSVLTVIKLLEVRGPELGRPYADTLESTKEVKNLKELRTQHQGRPYRIFFAFDPKRQA
VLLCGGDKTGDKRFYKRMIPIAEGEFLKHLEKEELH

Nucleotide

• Length: 351 bp

>T150134 NZ_CP064393:3716554-3717132 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTGTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTCCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAGGCCGCGCACCCGGACAAAGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCACCTCGACGC
GCCGCTGCGCGACCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGTGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin

Protein

• Length: 107 a.a.
• Molecular weight: 11569.03 Da
• Isoelectric Point: 4.8304

>AT150134 WP_163836089.1 NZ_CP048878:c6034915-6034595 [Spartinivicinus ruber]
MAKPLSELLKQVSPEVQAKASAKAAELLTEMTLAELRQSKDITQTELAEALSTTQPNIANVEKRSDVYLSTLRNYLHALG
GELEVVARFPDGSAVAINQYDNNHTT

Nucleotide

• Length: 321 bp

>AT150134 NZ_CP064393:3715912-3716466 [Pseudomonas aeruginosa]
ATGACCGAGCCTCTCCCTTCTTCGTCCCTGGGCCCCGCCCTGCGTCGCTGGCGCCTGCTGCACCGGGTCAAGCAAACGCA
TGCCGCCGAATTGCTCGGCGTGGCGCAATCGACCATCTCGCGCTGGGAGTCCGGTACCCAGGCGCTGCTGGTGGAGGAAC
GGGCACGCCTGGAGCGTCTGCTCGGCGCCCGCCTGGAAGCCGCCGCCGACCAGGCACTGGCCCGCCTGGTCGAGGCCAAC
CCGCAACCCGTGCACCTGATCTGCGACCTCACCCATCGCCTGTTGGCCTGTTCGCCGGCACGCGCCGCGCAATTCGGCGT
GCCTCTCGGCGAACTGCTCGACCGTTCGCTGTGGCCCTATTGCAGCGAGGAAATCCTCCGCCAGGAAGCCACCCTCGAGG
AACTCGGCTGGCGCGAACTGCTGGCACCGCCGGCGCTGGAGTTCGCCAGCGGAGCGAACGCCTCGGCCATCGTGCCGATC
CGGCGCAGCCGTTGCCGCTGGACCCGCATGACCCTCTCGGACGGACGCGCGGTGCGCCTGGTGGAAACCCTCTGA