Detailed information of TA system TA150121

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 1775101..1775318
• Replicon: chromosome
• Accession: NZ_CP048852
• Organism: Bacillus tequilensis strain EA-CB0015

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: A0A6H0WKE8
• Locus tag: G4P54_RS09375
• Protein ID: WP_032721653.1
• Coordinates: 1775142..1775318 (+)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	1775101..1775201 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G4P54_RS09360	1770922..1771824	-	903	WP_167872459.1	GIY-YIG nuclease family protein	-
G4P54_RS09365	1772009..1773883	-	1875	Protein_1782	hypothetical protein	-
G4P54_RS09370	1773923..1774117	-	195	WP_167872461.1	hypothetical protein	-
-	1775101..1775201	-	101	NuclAT_0	-	Antitoxin
-	1775101..1775201	-	101	NuclAT_0	-	Antitoxin
-	1775101..1775201	-	101	NuclAT_0	-	Antitoxin
-	1775101..1775201	-	101	NuclAT_0	-	Antitoxin
G4P54_RS09375	1775142..1775318	+	177	WP_032721653.1	hypothetical protein	Toxin
G4P54_RS09380	1775337..1775588	+	252	WP_167872462.1	hypothetical protein	-
G4P54_RS09385	1775633..1775794	+	162	WP_167872463.1	hypothetical protein	-
G4P54_RS09390	1775905..1777137	+	1233	WP_167872464.1	hypothetical protein	-
G4P54_RS09395	1777476..1779344	+	1869	WP_167872465.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1693758..1855230	161472

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-100)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6850.39 Da
• Isoelectric Point: 12.8833

>T150121 WP_032721653.1 NZ_CP048852:1775142-1775318 [Bacillus tequilensis]
VLEKVGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T150121 NZ_CP064391:c3667694-3667347 [Pseudomonas aeruginosa]
ATGTCCCCGGTCGTCATTCGTTTTACTGATACCGCAGAGCAAAGCATCGAAGACCAAGTCCACCACTTGGCTCCATTCCA
AGGTGAACAGGCTGCACTCCAGTCAGTACTGAGCCTTTTGGATGAGATTGAAGAGAAGATTTCACTTGCACCTAAAGGTT
ACCCAGTCAGCCAGCAGGCGAGTCTTCTGGGGGTGCTGAGCTATCGCGAGCTTAATACCGGCCCCTATCGTGTTTTTTAC
GAATTCCACGAAGAGCAAGGCGAGGTGGCAGTGATCTTGGTTTTGCGACAGAAGCAGAGCGTTGAGCAGCAATTGATCCG
CTACTGCTTGGTGGGGCCAATCGAGTGA

Antitoxin

Nucleotide

• Length: 101 bp

>AT150121 NZ_CP048852:c1775201-1775101 [Bacillus tequilensis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Structures

Toxin

• AlphaFold DB: A0A6H0WKE8

Antitoxin