Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5378814..5379469 Replicon chromosome
Accession NZ_CP048810
Organism Pseudomonas bijieensis strain L22-9

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag GN234_RS23745 Protein ID WP_176689164.1
Coordinates 5378814..5379158 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag GN234_RS23750 Protein ID WP_003205391.1
Coordinates 5379155..5379469 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN234_RS23720 5373830..5374777 + 948 WP_003205397.1 ubiquinol oxidase subunit II -
GN234_RS23725 5374781..5376811 + 2031 WP_109754836.1 cytochrome o ubiquinol oxidase subunit I -
GN234_RS23730 5376815..5377441 + 627 WP_109754835.1 cytochrome o ubiquinol oxidase subunit III -
GN234_RS23735 5377442..5377777 + 336 WP_025211927.1 cytochrome o ubiquinol oxidase subunit IV -
GN234_RS23740 5377789..5378676 + 888 WP_109754834.1 heme o synthase -
GN234_RS23745 5378814..5379158 + 345 WP_176689164.1 toxin Toxin
GN234_RS23750 5379155..5379469 + 315 WP_003205391.1 helix-turn-helix domain-containing protein Antitoxin
GN234_RS23755 5379707..5380411 - 705 WP_109754832.1 hypothetical protein -
GN234_RS23760 5380550..5381293 - 744 WP_109754831.1 DUF72 domain-containing protein -
GN234_RS23765 5381386..5382399 - 1014 WP_109754830.1 GGDEF domain-containing protein -
GN234_RS23770 5382643..5383560 - 918 WP_176689165.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(47-87)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13662.68 Da        Isoelectric Point: 9.2887

>T150034 WP_176689164.1 NZ_CP048810:5378814-5379158 [Pseudomonas bijieensis]
MRTLFFETTTFTATVGHYLTDDEYRLLQSYLLEHPEVGDVMPRTGGFRKLRWFDERRGKGKRGGLRVIYYWLMNDRQFWM
FAIYDKDELVNLTSEQEKTLKRAIEAELKVRGTL

Download         Length: 345 bp

>T150034 NZ_CP064377:c5012702-5012325 [Achromobacter xylosoxidans]
ATGATCCTGGTTGACACTTCCATCTGGATAGATCATTTATCCGACGGCGAGCCATGTCTGGTGCGCTTGCTGGAGGAAGA
AAGTGTATTGATGCACCCGTTCATCGCGGGTGAATTGGCGCTGGGTTCGTTGGGCCGGCGTGACGTTGTATTGGGTACGA
TGTCGCTATTGCCTCAAGTCGTGCGTGCGAGTCATGACGAAGTCATGCACTTTCTTCATAGCGAGAGATTGTTTGGAAAG
GGCATTGGTTATGTGGATTTACACTTGTTGGCGTCCACGCGACTGACACCTGGCGCGGCGCTATGGACCAGGGAAAAACG
GCTGCAGGCACTCGCCACCACCTTGAGCCTGGCGGTTGATCCCCCGAGATATCATTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11771.76 Da        Isoelectric Point: 9.8409

>AT150034 WP_003205391.1 NZ_CP048810:5379155-5379469 [Pseudomonas bijieensis]
MKKRDLFAEMMQGVEEMAAHREGKITLRQISIEDKPVPEVSAQEIVALRDKLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIKLVEKFPDMVERLGAV

Download         Length: 315 bp

>AT150034 NZ_CP064377:c5012898-5012689 [Achromobacter xylosoxidans]
GTGCGTACGACTGTGACGCTCGATGACGACCTGCTCGAATTGGCCCGTACCTATACGGGCGTCCAGGAGACATCGGCGCT
CGTAACGCGAGCGCTGACCCAGCTCGTGCAGAAAGAGGCCGCGAAGCGGCTGGCCAAGCTTGGTGGTAGTTCGCCCAAGT
TGAAGCCTATCCCGCGGCGGCAGACGGAAACCTGCAATGATCCTGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References