Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 4807107..4807779 Replicon chromosome
Accession NZ_CP048810
Organism Pseudomonas bijieensis strain L22-9

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag GN234_RS21050 Protein ID WP_176689018.1
Coordinates 4807107..4807472 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag GN234_RS21055 Protein ID WP_109754986.1
Coordinates 4807465..4807779 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN234_RS21040 4804257..4805051 - 795 WP_176689016.1 carbon-nitrogen hydrolase family protein -
GN234_RS21045 4805064..4806746 - 1683 WP_176689017.1 FAD-dependent oxidoreductase -
GN234_RS21050 4807107..4807472 + 366 WP_176689018.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GN234_RS21055 4807465..4807779 + 315 WP_109754986.1 XRE family transcriptional regulator Antitoxin
GN234_RS21060 4807802..4808263 - 462 WP_018607342.1 Lrp/AsnC family transcriptional regulator -
GN234_RS21065 4808300..4810624 - 2325 WP_176689615.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-106)

Antitoxin

HigA2-like, helix-turn-helix domain

(16-86)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13987.65 Da        Isoelectric Point: 5.2052

>T150033 WP_176689018.1 NZ_CP048810:4807107-4807472 [Pseudomonas bijieensis]
MKWDVEYTDEFEMWWSCLSETEQDSVQASVMLLGDAGPHLGFPHTSDIKGSRHGNLRELRVQHAGRPYRVLHAFDPRRCA
ILLIGGDKTGQDRWYQECVPLAERLYDEHLEALKREGFDNG

Download         Length: 366 bp

>T150033 NZ_CP064377:4898280-4898855 [Achromobacter xylosoxidans]
ATGAGGCATTCCCCCTTCACAGCCGTCTACGACGCATGCGTTTTGTATCCCGCGCCACTGCGGGACTTCCTGATGTGGCT
CGGCCTGTCCGGCCGCTTCAGGGCGCGGTGGAGTCAAGCCATCCATGAGGAGTGGAAACGCAACCTGTTGATCAAACGAC
CCGATCTCAACCGGGCGCAGGTCGACAGGACGTCCGATCTCATGGACAGGGCCATTCCGGACGGCGTGGTGGAGGGATAT
GAAGAGCTCGTGGCAGGCCTGACATTGCCCGATCCGGACGATCGGCACGTCCTGGCTGCGGCGATCCGCTGTGGTGCGAG
CGTGATCGTGACGTTCAACGAACGAGATTTCCCGAACGAGCTGCTGGCTGCGTACGGTATCGAAGCGCAGCACCCCGACG
AGTTCGTGGACAACCTGCTGGATCTGGATGCGGCCGCCGTCGTGTCAGCAGCGCAGCGCCAGCGTGCCCAGCTCAAGCAT
CCGCCAATCGACGTGGACTGCTTTCTCGAAATCCTGCTTCGCCAAGGCTTGGTGCAAACGACCAAAGTGCTGGCGACCTA
TCGCACCATCCTCTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12002.75 Da        Isoelectric Point: 9.9863

>AT150033 WP_109754986.1 NZ_CP048810:4807465-4807779 [Pseudomonas bijieensis]
MAKKFSDLIARRSPDSRARAETLYQKLRAEMPLHELRQAQELSQDALAKTLHINQAAVSKMERRTDMYISTLRNYIRAMG
GELEIIATFPEGQVRIENFAHQTQ

Download         Length: 315 bp

>AT150033 NZ_CP064377:4897813-4898283 [Achromobacter xylosoxidans]
ATGACCACCACCGCTGCCCAATCCAAGATGACCCTTCCCGCTGCGGCAGAGGTGAAGGCCGCCGTTCAGGGTCAACGTGC
CTTGGCGGCCTATCTGGCAACCCAGTTCGAGACGCAGCACATTCAGATCTTTGACGACCACAAGCAGGCGCATCAGGTGG
AGCTGCCCACCTCGGCTTTGCGCCTGCTTGTCGACATCCTGGCTGAACTGGCCGATGGCAACGCCGTGAAGGTGGTGCCC
GTTCACGCAGAGCTGACGACACAGGAGGCAGCCGATCTGCTCAACGTGTCCCGCCCCCATTTAGTCAAGCTGCTCGAGGA
TGGAGTGTTGGCATTTCACCGGACCGGCAAGCACCGCAGGGTGAGGTTCGCCGATCTGATGCAGTACAAGGAAGCGCGCG
AGCGCGCCAGTGAGCAGGCGATGGCCGAACTCGCTCAGCAGTCGCAAGAGTTGGGAATGGGGTACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References