Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 2067639..2068294 Replicon chromosome
Accession NZ_CP048629
Organism Pseudomonas sp. OIL-1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag G3M63_RS09645 Protein ID WP_163982879.1
Coordinates 2067639..2067983 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag G3M63_RS09650 Protein ID WP_163982880.1
Coordinates 2067980..2068294 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3M63_RS09635 2063469..2066705 - 3237 WP_163982875.1 HsdR family type I site-specific deoxyribonuclease -
G3M63_RS09640 2066822..2067382 - 561 WP_163982877.1 hypothetical protein -
G3M63_RS09645 2067639..2067983 + 345 WP_163982879.1 toxin Toxin
G3M63_RS09650 2067980..2068294 + 315 WP_163982880.1 helix-turn-helix domain-containing protein Antitoxin
G3M63_RS09655 2068422..2068571 - 150 WP_178100965.1 hypothetical protein -
G3M63_RS09660 2068711..2070012 - 1302 WP_163982882.1 restriction endonuclease subunit S -
G3M63_RS09665 2070044..2071618 - 1575 WP_163982884.1 type I restriction-modification system subunit M -
G3M63_RS09670 2072048..2072344 - 297 WP_163982886.1 hypothetical protein -
G3M63_RS09675 2072354..2072674 - 321 WP_163982888.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(45-88)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13279.21 Da        Isoelectric Point: 8.4649

>T149779 WP_163982879.1 NZ_CP048629:2067639-2067983 [Pseudomonas sp. OIL-1]
MKGIFIETSVFTARVGDYLTDEEYRHLQTEMLAHPECGDVMPRTGGFCKLRWADSRRGKGKRGGLRVVYYWLMGDGQFWM
FSIYDKDEMENLTADQEKQLKQAITKELSKRGTK

Download         Length: 345 bp

>T149779 NZ_CP064241:c5300497-5300114 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11927.94 Da        Isoelectric Point: 10.3373

>AT149779 WP_163982880.1 NZ_CP048629:2067980-2068294 [Pseudomonas sp. OIL-1]
MNKRNLFDEMMQGIDEMAAQREGKITLRHVTVENRPAPEVTAGEIVALRKKMKMSQKVFAMRIRTSAETLRNWEQDKAKP
NAQAALLIKLVEQYPDMVDRLASV

Download         Length: 315 bp

>AT149779 NZ_CP064241:c5300739-5300497 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References