Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4439146..4439801 Replicon chromosome
Accession NZ_CP048607
Organism Pseudomonas fluorescens strain DR133

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag GZ982_RS19825 Protein ID WP_163856795.1
Coordinates 4439146..4439490 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag GZ982_RS19830 Protein ID WP_003205391.1
Coordinates 4439487..4439801 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZ982_RS19800 4434160..4435107 + 948 WP_163856789.1 ubiquinol oxidase subunit II -
GZ982_RS19805 4435111..4437141 + 2031 WP_109754836.1 cytochrome o ubiquinol oxidase subunit I -
GZ982_RS19810 4437145..4437771 + 627 WP_163856792.1 cytochrome o ubiquinol oxidase subunit III -
GZ982_RS19815 4437772..4438107 + 336 WP_025211927.1 cytochrome o ubiquinol oxidase subunit IV -
GZ982_RS19820 4438119..4439006 + 888 WP_109754834.1 heme o synthase -
GZ982_RS19825 4439146..4439490 + 345 WP_163856795.1 toxin Toxin
GZ982_RS19830 4439487..4439801 + 315 WP_003205391.1 helix-turn-helix domain-containing protein Antitoxin
GZ982_RS19835 4440040..4440744 - 705 WP_109754832.1 hypothetical protein -
GZ982_RS19840 4440883..4441626 - 744 WP_163856798.1 DUF72 domain-containing protein -
GZ982_RS19845 4441719..4442732 - 1014 WP_109754830.1 GGDEF domain-containing protein -
GZ982_RS19850 4442968..4443870 - 903 WP_163856801.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(47-87)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13752.77 Da        Isoelectric Point: 8.3860

>T149731 WP_163856795.1 NZ_CP048607:4439146-4439490 [Pseudomonas fluorescens]
MRTLFFETTTFTATVGHYLTDDEYRLLQSYMLEHPEVGDVMPRTGGFRKLRWFDERRGKEKRGGLRVIYYWLMNDRQFWM
FAIYDKDELVNLTSEQEKTLKRAIEAELKVRGTL

Download         Length: 345 bp

>T149731 NZ_CP064230:c198078-197767 [Klebsiella pneumoniae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTAAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11771.76 Da        Isoelectric Point: 9.8409

>AT149731 WP_003205391.1 NZ_CP048607:4439487-4439801 [Pseudomonas fluorescens]
MKKRDLFAEMMQGVEEMAAHREGKITLRQISIEDKPVPEVSAQEIVALRDKLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIKLVEKFPDMVERLGAV

Download         Length: 315 bp

>AT149731 NZ_CP064230:c197770-197351 [Klebsiella pneumoniae]
ATGATTACCGACACTGCAAAAGCCATTGAAGCAACCAAACAACTCGTAGCTGCCGTCCCCTTCCTAGGGGGCAGTTCTTC
CGAGAGCGATTACCGCGAAGCGATGGAGCTGGTGGATTATCTGATCGAGAACGACGACGAGAACCCACTTATTGACTTCC
TGGCGAGTAAGATTGCCGACTATGAAGATAACAGCCCTCGTTTCGCTGAGTTCAACAAAGCTATTGCTGAAATACCAGTC
GGCGTTGCACTTCTGCGAACCCTGATTGACCAGCACAAGCTGTCTTATTCAGACCTTAAGGATGAGATCGGATCTAAATC
ATTGGTCAGCCAAATCCTGTCAGGGCAGCGCTCTTTGACCATCACTCACATAAAAGCTCTTTCCGCGCGCTTCGGTGTAA
AACCTGAGTGGTTCCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References