Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 1709272..1709792 Replicon chromosome
Accession NZ_CP048558
Organism Agrobacterium fabrum strain Kin001

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FY134_RS08535 Protein ID WP_080808022.1
Coordinates 1709272..1709541 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FY134_RS08540 Protein ID WP_080808019.1
Coordinates 1709538..1709792 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY134_RS08515 (FY134_08480) 1704307..1706001 - 1695 WP_092731507.1 iron ABC transporter permease -
FY134_RS08520 (FY134_08485) 1706011..1706994 - 984 WP_111808036.1 ABC transporter substrate-binding protein -
FY134_RS08525 (FY134_08490) 1707299..1708543 - 1245 WP_111808038.1 PLP-dependent aminotransferase family protein -
FY134_RS08530 (FY134_08495) 1708818..1709267 + 450 WP_092771026.1 RbsD/FucU family protein -
FY134_RS08535 (FY134_08500) 1709272..1709541 - 270 WP_080808022.1 Txe/YoeB family addiction module toxin Toxin
FY134_RS08540 (FY134_08505) 1709538..1709792 - 255 WP_080808019.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FY134_RS08545 (FY134_08510) 1709931..1710950 - 1020 WP_111808040.1 ketol-acid reductoisomerase -
FY134_RS08550 (FY134_08515) 1710998..1711651 - 654 WP_006311841.1 TetR/AcrR family transcriptional regulator -
FY134_RS08555 (FY134_08520) 1712055..1712960 - 906 WP_006311840.1 AraC family transcriptional regulator -
FY134_RS08560 (FY134_08525) 1713150..1714196 + 1047 WP_080808012.1 NAD(P)-dependent alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10611.15 Da        Isoelectric Point: 9.8742

>T149615 WP_080808022.1 NZ_CP048558:c1709541-1709272 [Agrobacterium fabrum]
MKLVWTLSSWDDYEFWQRTDARMVEKINDLIRNAKRTPFAGLGKPEPLKGDMAGYWSRRITAEHRFVYRVSGSGSEQRLE
IIQCRFHYL

Download         Length: 270 bp

>T149615 NZ_CP064187:716119-716484 [Rhizobium sp. 007]
ATGGTGAAAGCGCTCTTCGATACGAACATCCTTATCGACTATCTCAACGCCATACCGGAAGCCCGCGACGAGCTTGACCG
CTATGGACGCCGTGCCATCAGCGTCGTCACTTGGATGGAGGTGTTGATTGGCGCTGATCCCGACGTCGAAGCAGCGACGC
GAAGCTTCTTGAATAACTTCCAGATCATCGCGGTTGATAATGCGATAGCGGAAGGCGCTGTTCGCTTAAGACAGCACCAC
CGGATCAACTTGCCGGACGCGATAATCTGGTCGACCGCCGATGCGCATGCGTTGCTCCTGGTGACGCGCAACACCAAGGA
CTTTCCGGCGGATAATCCTGGAATCCGCGTCCCATATCTGCGTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9692.84 Da        Isoelectric Point: 4.6882

>AT149615 WP_080808019.1 NZ_CP048558:c1709792-1709538 [Agrobacterium fabrum]
MANVRFTEFRQNFATHFDRVLETRAPLLVTRQGKEAVVVLAEGEYESMQETLHLLSNPANASRLRASMDELERDDTIERD
PTEK

Download         Length: 255 bp

>AT149615 NZ_CP064187:715910-716125 [Rhizobium sp. 007]
ATGCGTATCCTGGTCGATATCGTCGAATCCGAGTTGAAGGCGCTGGATAAGATGGCGAAGAGCGAGAAGGTTTCCCGCGC
TTCGCTCATCCGCAAAGCTGTCAACGATTTTCTGGATCGTCATGATCGGACAAAAGAGGCAGAAGCTTTCGGGCTCTGGG
GTAATAGAAAGATCGATGGGCTCGAATACCAGGATAAAGTTCGAAGCGAATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References