Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1192019..1192718 Replicon chromosome
Accession NZ_CP048458
Organism Burkholderia multivorans strain P1Bm2011a

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag G0D87_RS20660 Protein ID WP_059786235.1
Coordinates 1192422..1192718 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID B9B077
Locus tag G0D87_RS20655 Protein ID WP_006397015.1
Coordinates 1192019..1192420 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G0D87_RS20635 1187714..1189066 - 1353 WP_105842813.1 LLM class flavin-dependent oxidoreductase -
G0D87_RS20640 1189063..1190124 - 1062 WP_206381911.1 MsnO8 family LLM class oxidoreductase -
G0D87_RS20645 1190156..1191097 - 942 WP_206381912.1 transporter substrate-binding domain-containing protein -
G0D87_RS20650 1191163..1191723 - 561 WP_155825035.1 GNAT family N-acetyltransferase -
G0D87_RS20655 1192019..1192420 - 402 WP_006397015.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
G0D87_RS20660 1192422..1192718 - 297 WP_059786235.1 type II toxin-antitoxin system MqsR family toxin Toxin
G0D87_RS20665 1192838..1193872 - 1035 WP_006397017.1 succinylglutamate desuccinylase/aspartoacylase family protein -
G0D87_RS20670 1193975..1194247 - 273 WP_012216969.1 hypothetical protein -
G0D87_RS20675 1194455..1195999 - 1545 WP_170935331.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(72-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11215.10 Da        Isoelectric Point: 9.1122

>T149538 WP_059786235.1 NZ_CP048458:c1192718-1192422 [Burkholderia multivorans]
MEKRTPHCKLPRVKALIEAGKVRLTASAVIGARQMGFTESETIDVVRALTPFEFHKSMTTYADHTIWQDVYRPCTMRGDV
YLKLTVVDDVLIVSFKER

Download         Length: 297 bp

>T149538 NZ_CP064126:c2485553-2485460 [Yersinia pestis]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14477.62 Da        Isoelectric Point: 7.0834

>AT149538 WP_006397015.1 NZ_CP048458:c1192420-1192019 [Burkholderia multivorans]
MKCPACGAAALVRDTRDIPYTYKGESTVIPHVTGEFCPACGESVLDVDEATRFGEAVSAFNRQVNATLVDPKFIATVRKK
LKLDQREAAEIFGGGVNAFSRYETGKTNPPLALVKLLKLLDRHPDLLDEVRAA

Download         Length: 402 bp

>AT149538 NZ_CP064126:2485459-2485553 [Yersinia pestis]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB B9B077

References