Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2521361..2521884 Replicon chromosome
Accession NZ_CP048415
Organism Algoriphagus sp. NBT04N3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag GYM62_RS10935 Protein ID WP_106567542.1
Coordinates 2521361..2521615 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GYM62_RS10940 Protein ID WP_144606316.1
Coordinates 2521633..2521884 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GYM62_RS10915 (GYM62_10910) 2516971..2518212 - 1242 WP_144606324.1 ABC transporter substrate-binding protein -
GYM62_RS10920 (GYM62_10915) 2518381..2518827 + 447 WP_144606322.1 DUF2721 domain-containing protein -
GYM62_RS10925 (GYM62_10920) 2518817..2519758 + 942 WP_144606320.1 glycerophosphodiester phosphodiesterase family protein -
GYM62_RS10930 (GYM62_10925) 2520139..2521152 + 1014 WP_144606318.1 GntG family PLP-dependent aldolase -
GYM62_RS10935 (GYM62_10930) 2521361..2521615 - 255 WP_106567542.1 Txe/YoeB family addiction module toxin Toxin
GYM62_RS10940 (GYM62_10935) 2521633..2521884 - 252 WP_144606316.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GYM62_RS10945 (GYM62_10940) 2522031..2522570 + 540 Protein_2172 AAA family ATPase -
GYM62_RS10950 2522930..2524243 - 1314 WP_219956415.1 HAD-IC family P-type ATPase -
GYM62_RS10955 2524216..2525190 - 975 WP_219956416.1 HAD-IC family P-type ATPase -
GYM62_RS10960 2525187..2525750 - 564 WP_219956417.1 cation-transporting P-type ATPase -
GYM62_RS10965 (GYM62_10950) 2525808..2526356 - 549 WP_219956418.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10411.95 Da        Isoelectric Point: 9.7323

>T149392 WP_106567542.1 NZ_CP048415:c2521615-2521361 [Algoriphagus sp. NBT04N3]
MKIIFLSTGWEDYLFWQQHDRKTLKKINELIKESIRTPFEGTGKPEPHKHNLSGWWSRRINLEHRLVYRVEHDSIYILQC
RYHY

Download         Length: 255 bp

>T149392 NZ_CP064064:9047-9343 [Brucella anthropi]
ATGGCCACTAAACGGCCTTTCCGGCTCGCTCCTGCCGCCAAGGCCGATCTTCGGAAGATATGGCGCTACACGGCTCGTCG
CTGGTCGTTGGAGCAGGCTGAAACCTATCAGGATCAGCTTTATGCTGCGTTCGAGGGTCTGGCCGCTGGGACGAAAAAAG
GCCGCGATGTCGATGTGCGACGGGGCTATCTTAAATACCCGGCAGGATCGCACATCGTCTATTTTAAGGATCGTGGCGAC
CGGATCGAGATTATCCGCGTCCTGCATGGCCGAATGGACGCGAGTCGGCACTTGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9810.11 Da        Isoelectric Point: 5.1695

>AT149392 WP_144606316.1 NZ_CP048415:c2521884-2521633 [Algoriphagus sp. NBT04N3]
MEITTYSNFRQHLKSFLDKVFHDRSPLFVTRANGEDVVVMSKTDYESMQETFYLLKSPKNAERLLRGIEEFEKGLGEEKN
LFE

Download         Length: 252 bp

>AT149392 NZ_CP064064:8809-9057 [Brucella anthropi]
ATGGCTGCTAGAAGTACGTCTATTTCCCTTGGCGATCACTTTGCCGGTTTTATCGACAGCCAGGTACAAACTGGCCGCTA
CGGCTCCGTTAGTGACGTTGTGCGGGCTGGACTTCGGCTACTTGAAGAACACGAGGCGAAGGTCAAGGCGCTGGAAGCTG
CCTTGATCGAGGGCGAGGAATCCGGCGAGCCTGAGCCATTCGACAACGAAGCGTTTAAAGCCGAAATGCGCGCCGAATAT
GGCCACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References