Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1087008..1087540 Replicon chromosome
Accession NZ_CP048289
Organism Streptacidiphilus sp. P02-A3a

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag GXP74_RS05065 Protein ID WP_182450214.1
Coordinates 1087286..1087540 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GXP74_RS05060 Protein ID WP_182450213.1
Coordinates 1087008..1087289 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GXP74_RS05040 1083158..1084132 + 975 WP_182450209.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
GXP74_RS05045 1084199..1084939 + 741 WP_182450210.1 ROK family protein -
GXP74_RS05050 1084974..1085546 - 573 WP_182450211.1 hypothetical protein -
GXP74_RS05055 1085736..1086809 + 1074 WP_182450212.1 redox-regulated ATPase YchF -
GXP74_RS05060 1087008..1087289 + 282 WP_182450213.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GXP74_RS05065 1087286..1087540 + 255 WP_182450214.1 Txe/YoeB family addiction module toxin Toxin
GXP74_RS05070 1088134..1088397 - 264 WP_182450215.1 type II toxin-antitoxin system RelE/ParE family toxin -
GXP74_RS05075 1088571..1089437 - 867 WP_182450216.1 isocitrate lyase/phosphoenolpyruvate mutase family protein -
GXP74_RS05080 1089707..1090171 + 465 WP_182450217.1 NUDIX domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-64)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10084.54 Da        Isoelectric Point: 8.4461

>T148958 WP_182450214.1 NZ_CP048289:1087286-1087540 [Streptacidiphilus sp. P02-A3a]
VRLVFEDQGWEDYTSWLKSDRKMLARINKLNEDVRRDPFAGLGKPEPLKYHLPGAWSRRIDEEHRLVYLVTDKEIVILAA
RYHY

Download         Length: 255 bp

>T148958 NZ_CP063910:652995-654317 [Klebsiella variicola]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGCACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCGCTGCCGCTGCAGTATGGCAATATCACCG
CCGACACGGTGTATCACTATTTTGATAACCTGCTACCCGACAGCCCGCAGGTCCGCGATCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTGGGACGGGATAGCGTAGGGGCGGTGACTCTGCTACCGCCGGG
GGAAGAGGCGCACCTCGAGGGGTTGCGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCCTACCAGT
CGGATATCCCTCTCGGGATGATTACCGGCCAGGATGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGGGCACTGGTGTATTCCGCAGGGCACCACGCCGACCACGCATATCATTAAACTGCCCATCGGCGAGAT
AAAGCAGCCTAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAACGAGTTTCTGTGCCTGGCGCTGGCCAGGGAACTGG
GCCTGGCGGTGCCGGAGGCAGAGATTATCACCACGCCGCGGATCCGCGCGCTGGCGGTGACCCGCTTTGACCGGCGCTGG
GCGCAGGAGGGGCGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCCTTTGGCATCCCGTCGTCGATGAAATA
TGAATCTGACGGCGGGCCGGGTATTGCGGCAATCATGGCCTTTCTGCTGGGCTCCAGTGAAGCCCTGAAAGATCGCGCAG
ACTTTATGAAATTCATGGTTTTTCAGTGGCTGGTTGGGGCAACGGACGGGCATGCGAAGAACTTCTCGCTCTTTTTGCTG
CCCGGTGGCAGCTACCGTCTAACGCCGTTCTACGACATCATTTCGGCGTTTCCGGTGCTGGGAGGCACGGGACTGCATCT
GCGCGACCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGGAAAACAGAGATTAACGCTATCTATCCGCGTCATT
TTCTGGCAACCGCCAAAGCGGTGAACTTTCCTGGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGTTCGCCGGACGCTGCCGGCGGACTTTTCCACCCACGTCTGGCGGGCCATTACGGAAAATATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGTTATAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10173.51 Da        Isoelectric Point: 5.6358

>AT148958 WP_182450213.1 NZ_CP048289:1087008-1087289 [Streptacidiphilus sp. P02-A3a]
MSITASEARKELFPLIKKVNENHEAIEIVSKHGNAVLVSAEDYMALREGSYLLRSPANARRLLKAYENALSHVNVSEREL
IDPESPDAGAGVA

Download         Length: 282 bp

>AT148958 NZ_CP063910:652729-652995 [Klebsiella variicola]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTATCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCGACACTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTAGGGGTGGTGATGACGCTGAACGCCAAAGCCACAGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References