Detailed information of TA system TA148284

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 186435..186617
• Replicon: chromosome
• Accession: NZ_CP047849
• Organism: Staphylococcus aureus strain UP_403

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3S76_RS01090
• Protein ID: WP_001801861.1
• Coordinates: 186522..186617 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	186435..186494 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S76_RS01075	185573..185950	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
E3S76_RS01080	186144..186320	+	177	Protein_179	transposase	-
E3S76_RS01085	186298..186399	-	102	WP_001791893.1	hypothetical protein	-
-	186435..186494	+	60	-	-	Antitoxin
E3S76_RS01090	186522..186617	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
E3S76_RS01095	186820..186963	+	144	WP_001549059.1	transposase	-
E3S76_RS01100	187567..187950	+	384	WP_000070811.1	hypothetical protein	-
E3S76_RS01105	187961..188137	+	177	WP_000375476.1	hypothetical protein	-
E3S76_RS01110	188139..188324	+	186	WP_000809857.1	hypothetical protein	-
E3S76_RS01115	188438..189079	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
E3S76_RS01120	189297..189848	-	552	WP_000414205.1	hypothetical protein	-
E3S76_RS01125	189946..190290	-	345	WP_000627551.1	DUF3969 family protein	-
E3S76_RS01130	190331..190957	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	127100..223988	96888

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T148284 WP_001801861.1 NZ_CP047849:c186617-186522 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T148284 NZ_CP063487:c1304693-1304343 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACACGCCCGGCAGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGAAATAA

Antitoxin

Nucleotide

• Length: 60 bp

>AT148284 NZ_CP047849:186435-186494 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin