Detailed information of TA system TA148267

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 218813..218993
• Replicon: chromosome
• Accession: NZ_CP047847
• Organism: Staphylococcus aureus strain UP_522

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3S80_RS01405
• Protein ID: WP_001801861.1
• Coordinates: 218898..218993 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	218813..218870 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S80_RS01390	214420..215685	+	1266	WP_000072555.1	restriction endonuclease subunit S	-
E3S80_RS01395	215724..216574	+	851	Protein_243	DNA adenine methylase	-
E3S80_RS01400	216552..218247	+	1696	Protein_244	hypothetical protein	-
-	218813..218870	+	58	-	-	Antitoxin
E3S80_RS01405	218898..218993	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
E3S80_RS01410	219445..219891	+	447	WP_000747805.1	DUF1433 domain-containing protein	-
E3S80_RS01415	220075..220631	+	557	Protein_247	ImmA/IrrE family metallo-endopeptidase	-
E3S80_RS01420	220763..221515	-	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
E3S80_RS01425	221542..222285	-	744	WP_175393121.1	exotoxin	-
E3S80_RS01430	222312..222938	-	627	WP_000669028.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	197538..225496	27958

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T148267 WP_001801861.1 NZ_CP047847:c218993-218898 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T148267 NZ_CP063483:3014241-3014528 [Escherichia coli]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT148267 NZ_CP047847:218813-218870 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin