Detailed information of TA system TA148229

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 175674..175854
• Replicon: chromosome
• Accession: NZ_CP047841
• Organism: Staphylococcus aureus strain UP_644

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3S84_RS01055
• Protein ID: WP_001801861.1
• Coordinates: 175759..175854 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	175674..175731 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S84_RS01040	171280..172545	+	1266	WP_000072555.1	restriction endonuclease subunit S	-
E3S84_RS01045	172584..173434	+	851	Protein_172	DNA adenine methylase	-
E3S84_RS01050	173412..175108	+	1697	Protein_173	hypothetical protein	-
-	175674..175731	+	58	-	-	Antitoxin
E3S84_RS01055	175759..175854	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
E3S84_RS01060	175999..176224	+	226	Protein_175	hypothetical protein	-
E3S84_RS01065	176306..176752	+	447	WP_000747805.1	DUF1433 domain-containing protein	-
E3S84_RS01070	176936..177492	+	557	Protein_177	ImmA/IrrE family metallo-endopeptidase	-
E3S84_RS01075	177624..178376	-	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
E3S84_RS01080	178403..179146	-	744	WP_175393121.1	exotoxin	-
E3S84_RS01085	179173..179799	-	627	WP_000669028.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	154396..182357	27961

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T148229 WP_001801861.1 NZ_CP047841:c175854-175759 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T148229 NZ_CP063476:4767127-4767462 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATACGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTCTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTGCTGATTGGGTAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT148229 NZ_CP047841:175674-175731 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin