Detailed information of TA system TA148210

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1074625..1074822
• Replicon: chromosome
• Accession: NZ_CP047839
• Organism: Staphylococcus aureus strain UP_678

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: E3S85_RS05395
• Protein ID: WP_000623369.1
• Coordinates: 1074715..1074822 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1074625..1074662 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S85_RS05360	1069818..1070105	-	288	WP_000410718.1	hypothetical protein	-
E3S85_RS05365	1070446..1070736	+	291	WP_001791476.1	hypothetical protein	-
E3S85_RS05370	1070824..1071465	-	642	WP_000571183.1	ABC transporter ATP-binding protein	-
E3S85_RS05375	1071462..1071782	-	321	WP_000873929.1	YxeA family protein	-
E3S85_RS05380	1071785..1073749	-	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
E3S85_RS05385	1073793..1074065	-	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
E3S85_RS05390	1074075..1074176	-	102	WP_001790623.1	hypothetical protein	-
-	1074625..1074662	+	38	-	-	Antitoxin
E3S85_RS05395	1074715..1074822	-	108	WP_000623369.1	putative holin-like toxin	Toxin
E3S85_RS05400	1075093..1075695	-	603	WP_160176022.1	CPBP family intramembrane metalloprotease	-
E3S85_RS05405	1075710..1075886	-	177	WP_000214898.1	YkvS family protein	-
E3S85_RS05410	1076085..1077071	+	987	WP_000668820.1	lipoate--protein ligase	-
E3S85_RS05415	1077152..1077370	-	219	WP_000876825.1	IDEAL domain-containing protein	-
E3S85_RS05420	1077580..1078149	+	570	WP_031775450.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T148210 WP_000623369.1 NZ_CP047839:c1074822-1074715 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T148210 NZ_CP063476:844343-844446 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Nucleotide

• Length: 38 bp

>AT148210 NZ_CP047839:1074625-1074662 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin