Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2607556..2607835 Replicon chromosome
Accession NZ_CP047820
Organism Staphylococcus aureus strain UP_1395

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag E3T05_RS12850 Protein ID WP_001802298.1
Coordinates 2607556..2607660 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2607656..2607835 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3T05_RS12825 2602940..2603722 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
E3T05_RS12830 2603790..2604647 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
E3T05_RS12835 2605352..2605444 - 93 WP_001790138.1 hypothetical protein -
E3T05_RS12840 2605733..2606869 + 1137 WP_000115564.1 SAP domain-containing protein -
E3T05_RS12845 2606912..2607395 + 484 Protein_2481 recombinase family protein -
E3T05_RS12850 2607556..2607660 + 105 WP_001802298.1 hypothetical protein Toxin
- 2607656..2607835 - 180 - - Antitoxin
E3T05_RS12855 2608160..2609251 - 1092 WP_000495671.1 lytic regulatory protein -
E3T05_RS12860 2609517..2610497 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
E3T05_RS12865 2610499..2610819 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
E3T05_RS12870 2610971..2611636 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T148108 WP_001802298.1 NZ_CP047820:2607556-2607660 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T148108 NZ_CP063441:1769024-1769127 [Enterobacter asburiae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 180 bp

>AT148108 NZ_CP047820:c2607835-2607656 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References