Detailed information of TA system TA148100

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 180830..181012
• Replicon: chromosome
• Accession: NZ_CP047820
• Organism: Staphylococcus aureus strain UP_1395

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3T05_RS01080
• Protein ID: WP_001801861.1
• Coordinates: 180917..181012 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	180830..180889 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T05_RS01065	179968..180345	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
E3T05_RS01070	180539..180715	+	177	Protein_176	transposase	-
E3T05_RS01075	180693..180794	-	102	WP_001791893.1	hypothetical protein	-
-	180830..180889	+	60	-	-	Antitoxin
E3T05_RS01080	180917..181012	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
E3T05_RS01085	181215..181358	+	144	WP_001549059.1	transposase	-
E3T05_RS01090	181962..182345	+	384	WP_000070811.1	hypothetical protein	-
E3T05_RS01095	182356..182532	+	177	WP_000375476.1	hypothetical protein	-
E3T05_RS01100	182534..182719	+	186	WP_000809857.1	hypothetical protein	-
E3T05_RS01105	182833..183474	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
E3T05_RS01110	183692..184243	-	552	WP_000414205.1	hypothetical protein	-
E3T05_RS01115	184341..184685	-	345	WP_000627551.1	DUF3969 family protein	-
E3T05_RS01120	184726..185352	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T148100 WP_001801861.1 NZ_CP047820:c181012-180917 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T148100 NZ_CP063440:c3353175-3352237 [Proteus mirabilis]
ATGGATAAAGATAGCCCATATTACAAACAGGTTTCTTTGCTCATAAGAATGCTGCCTGTGGTAGCAACAGAGACGGTTTT
TGCACTTAAAGGTGGCACCGCCATTAATTTATTTGTGAGAGATTTTCCTCGGTTATCTGTAGATATTGATCTTGCTTATC
TTCCACTTGAACCAAGAGATGAGGCTTTGATTAATGTCAGGGCTGCATTGCAGCGCATTACAGACAGAATCAATACTCAA
CCAGATATCAGAGCGGCATTTCAGGATAATAAAGCTGATGAACTGAGAATAATTGTATCAAGTCCGGTTGCGACGATCAA
AATTGAAGTGTCGCCCGTCGCCAGAGGTACATTGCATAGTGCAGAAATAATGGCAGTTCAAGAGTCTGTTGAATACGAGT
TTGGTTATGCTGAGATTCAGGTAGTCAGTCTTCCCGATCTGTATGGTGGGAAATTGTGTGCTGCAATGGATCGCCAACAT
CCTCGCGACTTATTTGATGTGCGTATGTTACTTGGCAGTGAAGGGGTTTCGAGAGAGATTTTAGTGGGTTTTTTAACCTA
TACATTAAGTCATCCTCGGCCTATTAATGAAGTCATGTCGCCAAACTGGCAGCCGCTGAATGAGAAATTTCAGGCAGAAT
TTGATGGAATGACTTTTGAAAAAGTTGAATGCGAAGACTTAGCTTCTGTTAGGCCTATGATGTTAACTTCGCTGCAAAAA
CATTTCACAGAAAGGGATTATGCTTTCCTTATGTCATTCAAAAGAGGGCAACCTGACTGGGCATTGTTTGACTATCCTAA
TGCAGCAGACTTGCCAGCGATTCGTTGGAAGTTGCAGAACATAAACAAATTGGCAAAGAATCAAGCAAAACATCAAGAGC
AATTAGATAAATTGAAGCAAGTGCTTGATGATTGGCTTGTTAACGCAAACGCCGAGTAA

Antitoxin

Nucleotide

• Length: 60 bp

>AT148100 NZ_CP047820:180830-180889 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin