Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2587155..2587433 Replicon chromosome
Accession NZ_CP047817
Organism Staphylococcus aureus strain UP_1433

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag E3T06_RS12675 Protein ID WP_001802298.1
Coordinates 2587155..2587259 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2587255..2587433 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3T06_RS12660 2583952..2584734 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
E3T06_RS12665 2584802..2585659 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
E3T06_RS12670 2586317..2586475 - 159 WP_001792784.1 hypothetical protein -
E3T06_RS12675 2587155..2587259 + 105 WP_001802298.1 hypothetical protein Toxin
- 2587255..2587433 - 179 - - Antitoxin
E3T06_RS12680 2587692..2588783 - 1092 WP_000495669.1 hypothetical protein -
E3T06_RS12685 2589049..2590026 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
E3T06_RS12690 2590028..2590348 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
E3T06_RS12695 2590500..2591165 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T148091 WP_001802298.1 NZ_CP047817:2587155-2587259 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T148091 NZ_CP063427:1980953-1981055 [Citrobacter sp. BDA59-3]
GCATGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 179 bp

>AT148091 NZ_CP047817:c2587433-2587255 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References