Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2395532..2395716 Replicon chromosome
Accession NZ_CP047815
Organism Staphylococcus aureus strain UP_1484

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag E3T08_RS11780 Protein ID WP_000482647.1
Coordinates 2395609..2395716 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2395532..2395592 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3T08_RS11765 2390986..2391153 - 168 WP_001792506.1 hypothetical protein -
E3T08_RS11770 2391384..2393117 - 1734 WP_000486496.1 ABC transporter ATP-binding protein/permease -
E3T08_RS11775 2393142..2394905 - 1764 WP_001064836.1 ABC transporter ATP-binding protein/permease -
- 2395532..2395592 + 61 - - Antitoxin
E3T08_RS11780 2395609..2395716 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
E3T08_RS11785 2395850..2396236 - 387 WP_000779360.1 flippase GtxA -
E3T08_RS11790 2396494..2397636 + 1143 WP_001176863.1 glycerate kinase -
E3T08_RS11795 2397696..2398355 + 660 WP_000831295.1 hypothetical protein -
E3T08_RS11800 2398537..2399748 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
E3T08_RS11805 2399871..2400344 - 474 WP_000456492.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T148076 WP_000482647.1 NZ_CP047815:c2395716-2395609 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T148076 NZ_CP063424:c298002-297751 [Actinobacillus pleuropneumoniae]
ATGCAAGCAATAACCTACACAGAAGCACGCCAAAATCTAGCCGGTACAATGTCAAAAGTAGCAGAAGATTTTGAGCCTAT
TTTAATTACAAGAAGCAAGGGCGGAAATTGCGTACTTATGTCGTATGAGCAGTATAGTTCACTTGAAGAAACCGCCTATT
TAATGCGTTCCCCGGCTAACGCTCAAAGATTACTAGACAGCATGGCAGAATTGAAGCAAGGGAAAGGCATTGAAAGAGAG
CTAATCGAATGA

Antitoxin


Download         Length: 61 bp

>AT148076 NZ_CP047815:2395532-2395592 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References