Detailed information of TA system TA148034

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1328705..1328968
• Replicon: chromosome
• Accession: NZ_CP047809
• Organism: Staphylococcus aureus strain UP_1591

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: E3T14_RS06670
• Protein ID: WP_001802298.1
• Coordinates: 1328864..1328968 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF4
Locus tag	-
Coordinates	1328705..1328869 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T14_RS06650	1324888..1325553	-	666	WP_001024094.1	SDR family oxidoreductase	-
E3T14_RS06655	1325705..1326025	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
E3T14_RS06660	1326027..1327007	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
E3T14_RS06665	1327273..1328364	+	1092	WP_000495671.1	lytic regulatory protein	-
-	1328705..1328869	+	165	-	-	Antitoxin
E3T14_RS06670	1328864..1328968	-	105	WP_001802298.1	hypothetical protein	Toxin
E3T14_RS06675	1329129..1329612	-	484	Protein_1279	recombinase family protein	-
E3T14_RS06680	1329655..1330791	-	1137	WP_000115562.1	SAP domain-containing protein	-
E3T14_RS06685	1331080..1331172	+	93	WP_001790138.1	hypothetical protein	-
E3T14_RS06690	1331877..1332734	-	858	WP_000370924.1	Cof-type HAD-IIB family hydrolase	-
E3T14_RS06695	1332802..1333584	-	783	WP_000908177.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T148034 WP_001802298.1 NZ_CP047809:c1328968-1328864 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T148034 NZ_CP063397:1561401-1561610 [Rhizobium sp. SL42]
GTGAGCTCGTACAGCCTTCGCCCGTCGGCAGAGGCTGATCTCGAAGAGATCTGGGACTACACCGCCGAAATCTGGTCCGT
GACACAGGCCGAGCACTATGTCTCTGACATCTTTGCGTCGATTAGCCATCTGGTCGCCAACCCACATCTGGGGCGGCCGG
TTTCTGGCTACATTCAAACTATCGTAGATACAAAGTCGGGCACCACCTGA

Antitoxin

Nucleotide

• Length: 165 bp

>AT148034 NZ_CP047809:1328705-1328869 [Staphylococcus aureus]
GTAGCAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin