Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2247032..2247216 Replicon chromosome
Accession NZ_CP047807
Organism Staphylococcus aureus strain UP_1612

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag E3T15_RS11005 Protein ID WP_000482647.1
Coordinates 2247032..2247139 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2247156..2247216 (-)

Genomic Context


E3T15_RS10980E3T15_RS11000E3T15_RS11005E3T15_RS11010E3T15_RS11015E3T15_RS11020E3T15_RS10985E3T15_RS10990E3T15_RS10995--
Location: 2242404..2242877 (474 bp)
Type: Others
Protein ID: WP_000456489.1
Location: 2246512..2246898 (387 bp)
Type: Others
Protein ID: WP_000779360.1
Location: 2247032..2247139 (108 bp)
Type: Toxin
Protein ID: WP_000482647.1
Location: 2247767..2249530 (1764 bp)
Type: Others
Protein ID: WP_001064816.1
Location: 2249555..2251288 (1734 bp)
Type: Others
Protein ID: WP_000486494.1
Location: 2251519..2251686 (168 bp)
Type: Others
Protein ID: WP_001790576.1
Location: 2243000..2244211 (1212 bp)
Type: Others
Protein ID: WP_001192075.1
Location: 2244393..2245052 (660 bp)
Type: Others
Protein ID: WP_000831298.1
Location: 2245112..2246254 (1143 bp)
Type: Others
Protein ID: WP_001176863.1
Location: 2247156..2247216 (61 bp)
Type: Antitoxin
Protein ID: -
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
E3T15_RS109802242404..2242877+474WP_000456489.1GyrI-like domain-containing protein-
E3T15_RS109852243000..2244211-1212WP_001192075.1multidrug effflux MFS transporter-
E3T15_RS109902244393..2245052-660WP_000831298.1membrane protein-
E3T15_RS109952245112..2246254-1143WP_001176863.1glycerate kinase-
E3T15_RS110002246512..2246898+387WP_000779360.1flippase GtxA-
E3T15_RS110052247032..2247139+108WP_000482647.1type I toxin-antitoxin system Fst family toxinToxin
-2247156..2247216-61--Antitoxin
E3T15_RS110102247767..2249530+1764WP_001064816.1ABC transporter ATP-binding protein/permease-
E3T15_RS110152249555..2251288+1734WP_000486494.1ABC transporter ATP-binding protein/permease-
E3T15_RS110202251519..2251686+168WP_001790576.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T148016 WP_000482647.1 NZ_CP047807:2247032-2247139 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T148016 NZ_CP063394:1897783-1898370 [Pseudomonas aeruginosa]
ATGTCGAGGAGGGCGCCCATGTTCAAGCCGCTACCGATCACCCTGCAGCGCGGAGCCTTGCGTCTCGAGCCGCTGGTGGA
AGCGGACATTCCCGAGCTGGTGAGCCTCGCCGAAGCCAACCGCGAGGCGCTGCAGTACATGGACGGACCGACGCGGCCGG
ACTGGTACCGCCAGAGCCTCGCCGAGCAGCGCGAGGGCAGGGCGTTGCCGCTCGCCGTCCGCCTCGGTGTGCAACTGGTC
GGGACCACGCGCTTCGCCGAGTTCCTTCCCGCCTTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGACCAGGCCCAGCA
CGGCAGCGGCCTGAACCGCATGATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACCTGCGCATGGTCCGCGTGCAGC
TCAGCACGGCGGCGAGCAACCTGCGCGCCCAGGGCGCCATCGACAAGCTCGGCGCGCAGCGCGAGGGCGTGCTGCGCAAC
CACCGGCGGCTGGCCGGCGGGCGGCTAGACGACACCTTCGTCTACAGCATCACCGACCACGAATGGCCGCAGGTCAAGGC
GGCGCTGGAAGCCAGCTTCACCGGCTGA

Antitoxin


Download         Length: 61 bp

>AT148016 NZ_CP047807:c2247216-2247156 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A2P7CQJ7


Antitoxin

Download structure file

References