Detailed information of TA system TA148001

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2688228..2688490
• Replicon: chromosome
• Accession: NZ_CP047805
• Organism: Staphylococcus aureus strain UP_1654

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: E3T17_RS13185
• Protein ID: WP_073392962.1
• Coordinates: 2688228..2688332 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	2688327..2688490 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T17_RS13170	2685024..2685806	+	783	WP_000908186.1	ABC transporter ATP-binding protein	-
E3T17_RS13175	2685874..2686731	+	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
E3T17_RS13180	2687390..2687548	-	159	WP_001792784.1	hypothetical protein	-
E3T17_RS13185	2688228..2688332	+	105	WP_073392962.1	hypothetical protein	Toxin
-	2688327..2688490	-	164	-	-	Antitoxin
E3T17_RS13190	2688758..2690404	-	1647	WP_000277709.1	IS1182-like element ISSau3 family transposase	-
E3T17_RS13195	2690692..2691783	-	1092	WP_000495684.1	hypothetical protein	-
E3T17_RS13200	2692049..2693029	-	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
E3T17_RS13205	2693031..2693351	-	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2688758..2690404	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T148001 WP_073392962.1 NZ_CP047805:2688228-2688332 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T148001 NZ_CP063391:c5337332-5336922 [Pseudomonas aeruginosa]
ATGCTCAAGTTCATGCTTGACACCAACATCTGCATCTTCACTATCAAGAACCGCCCGCAAGAGGTGCGCGAGGCGTTCCT
GCGCCACCACGACCAGATGTGCATCAGCACCGTGACGCTGATGGAGCTGATCTACGGCGCAGAGAAGTCCTCGAACCCCT
CGCGCAATCTTGCAGACGTGGAAGGCTTCGCTGCTCGTCTGGAGGTGCTCAAGTACGACCAGGAAGCTGCCGCCCACACC
GGCCAGCTCCGCGCTGAACTGGCCCGCCTCGGCAAGCAAATCGGCCCCTATGACCAGATGATCGCCGGACACGCCCGCTC
TCAGGGCCTGATCGTGGTCACCAATAACCGCCGCGAGTTCGACCGCGTACCCGGCTTGAGAGTTGAGGATTGGGTCACCC
CAATCGTATAG

Antitoxin

Nucleotide

• Length: 164 bp

>AT148001 NZ_CP047805:c2688490-2688327 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Structures

Antitoxin