Detailed information of TA system TA147940

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1559136..1559316
• Replicon: chromosome
• Accession: NZ_CP047802
• Organism: Staphylococcus aureus strain UP_1442

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3S67_RS07695
• Protein ID: WP_001801861.1
• Coordinates: 1559136..1559231 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1559259..1559316 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S67_RS07665	1554299..1554949	+	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-
E3S67_RS07670	1555030..1556025	+	996	WP_000070642.1	DUF4352 domain-containing protein	-
E3S67_RS07675	1556100..1556726	+	627	WP_000669024.1	hypothetical protein	-
E3S67_RS07680	1556767..1557108	+	342	WP_000627540.1	DUF3969 family protein	-
E3S67_RS07685	1557209..1557781	+	573	WP_000414216.1	hypothetical protein	-
E3S67_RS07690	1557979..1558991	-	1013	Protein_1506	IS3 family transposase	-
E3S67_RS07695	1559136..1559231	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1559259..1559316	-	58	-	-	Antitoxin
E3S67_RS07700	1559354..1559455	+	102	WP_001792025.1	hypothetical protein	-
E3S67_RS07705	1559433..1559594	-	162	Protein_1509	transposase	-
E3S67_RS07710	1559585..1560079	-	495	Protein_1510	transposase	-
E3S67_RS07715	1560531..1561760	-	1230	WP_160200067.1	restriction endonuclease subunit S	-
E3S67_RS07720	1561753..1563309	-	1557	WP_000028669.1	type I restriction-modification system subunit M	-
E3S67_RS07725	1563473..1563607	-	135	WP_001791797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T147940 WP_001801861.1 NZ_CP047802:1559136-1559231 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147940 NZ_CP063370:c41662-41381 [Escherichia coli]
ATGATGGAGATATTCTGGACCATGCTGGCCAGCCAGGACAGGAAGCGCATTCGTGAGTACATTGCGGAGCAGAACCTGAT
GGCCGCCATTGAACTGGACGAACGGATTGGTTATTCAGCCAGCAGCCTGGCCGGGCAGCCGTATAAAGGCCGCAACGGTC
GTGTGGAAGGTACCCGGGAACTGGTTATTCACCCGCATTTTGTTCTGGTTTATGAGGTCGACAGCCAGTGGGGAAAAGTG
TATATCCTGCGAGTATTGCATACTGCACAGAAGTGGCCATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT147940 NZ_CP047802:c1559316-1559259 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin