Detailed information of TA system TA147926

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1159447..1159644
• Replicon: chromosome
• Accession: NZ_CP047801
• Organism: Staphylococcus aureus strain UP_248

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: E3S70_RS05965
• Protein ID: WP_000623369.1
• Coordinates: 1159537..1159644 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1159447..1159484 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S70_RS05930	1154640..1154927	-	288	WP_000410718.1	hypothetical protein	-
E3S70_RS05935	1155268..1155558	+	291	WP_001791476.1	hypothetical protein	-
E3S70_RS05940	1155646..1156287	-	642	WP_000571191.1	ABC transporter ATP-binding protein	-
E3S70_RS05945	1156284..1156604	-	321	WP_000873929.1	YxeA family protein	-
E3S70_RS05950	1156607..1158571	-	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
E3S70_RS05955	1158615..1158887	-	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
E3S70_RS05960	1158897..1158998	-	102	WP_001790623.1	hypothetical protein	-
-	1159447..1159484	+	38	-	-	Antitoxin
E3S70_RS05965	1159537..1159644	-	108	WP_000623369.1	putative holin-like toxin	Toxin
E3S70_RS05970	1159915..1160517	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
E3S70_RS05975	1160532..1160708	-	177	WP_000214898.1	YkvS family protein	-
E3S70_RS05980	1160907..1161893	+	987	WP_000668820.1	lipoate--protein ligase	-
E3S70_RS05985	1161974..1162192	-	219	WP_000876825.1	IDEAL domain-containing protein	-
E3S70_RS05990	1162402..1162971	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T147926 WP_000623369.1 NZ_CP047801:c1159644-1159537 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T147926 NZ_CP063369:1174412-1175734 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGTGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin

Nucleotide

• Length: 38 bp

>AT147926 NZ_CP047801:1159447-1159484 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin