Detailed information of TA system TA147842

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2166244..2166522
• Replicon: chromosome
• Accession: NZ_CP047796
• Organism: Staphylococcus aureus strain UP_462

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: E3S78_RS10345
• Protein ID: WP_073392962.1
• Coordinates: 2166244..2166348 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2166344..2166522 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S78_RS10330	2163040..2163822	+	783	WP_000908186.1	ABC transporter ATP-binding protein	-
E3S78_RS10335	2163890..2164747	+	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
E3S78_RS10340	2165406..2165564	-	159	WP_001792784.1	hypothetical protein	-
E3S78_RS10345	2166244..2166348	+	105	WP_073392962.1	hypothetical protein	Toxin
-	2166344..2166522	-	179	-	-	Antitoxin
E3S78_RS10350	2166774..2168420	-	1647	WP_000277741.1	IS1182-like element ISSau3 family transposase	-
E3S78_RS10355	2168708..2169799	-	1092	WP_000495684.1	hypothetical protein	-
E3S78_RS10360	2170065..2171045	-	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
E3S78_RS10365	2171047..2171367	-	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2166774..2168420	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T147842 WP_073392962.1 NZ_CP047796:2166244-2166348 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T147842 NZ_CP063334:57099-57479 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATTGCGCTTCATGATGCGAATATAAGCCGCTACGGCGGCCTGCCGGGAATGTC
AGATCCGGGTAGGGCAGAGGCCATTATCGGGAGAGTTCAGGCCAGAGTTGCCTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACAGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGCGCG
CTGCTATTTCTACGCCGTAACGGGGTGCAGGTATTTGATTCACCTGAACTGGCAGACCTTACTGTAGGCGCTGCGACTGG
CGAGATATCTGTATCTTCTGTCGCCGACACGTTACGTAGATTGTATGGTTCTGCGGAGTAG

Antitoxin

Nucleotide

• Length: 179 bp

>AT147842 NZ_CP047796:c2166522-2166344 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Structures

Antitoxin