Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprG-sprF/- |
Location | 2166244..2166506 | Replicon | chromosome |
Accession | NZ_CP047796 | ||
Organism | Staphylococcus aureus strain UP_462 |
Toxin (Protein)
Gene name | SprG3 | Uniprot ID | - |
Locus tag | E3S78_RS10345 | Protein ID | WP_073392962.1 |
Coordinates | 2166244..2166348 (+) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | SprF2 | ||
Locus tag | - | ||
Coordinates | 2166343..2166506 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
E3S78_RS10330 | 2163040..2163822 | + | 783 | WP_000908186.1 | ABC transporter ATP-binding protein | - |
E3S78_RS10335 | 2163890..2164747 | + | 858 | WP_000370937.1 | Cof-type HAD-IIB family hydrolase | - |
E3S78_RS10340 | 2165406..2165564 | - | 159 | WP_001792784.1 | hypothetical protein | - |
E3S78_RS10345 | 2166244..2166348 | + | 105 | WP_073392962.1 | hypothetical protein | Toxin |
- | 2166343..2166506 | - | 164 | - | - | Antitoxin |
E3S78_RS10350 | 2166774..2168420 | - | 1647 | WP_000277741.1 | IS1182-like element ISSau3 family transposase | - |
E3S78_RS10355 | 2168708..2169799 | - | 1092 | WP_000495684.1 | hypothetical protein | - |
E3S78_RS10360 | 2170065..2171045 | - | 981 | WP_000019741.1 | CDF family zinc efflux transporter CzrB | - |
E3S78_RS10365 | 2171047..2171367 | - | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 2166774..2168420 | 1646 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3920.80 Da Isoelectric Point: 5.5724
>T147841 WP_073392962.1 NZ_CP047796:2166244-2166348 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T147841 NZ_CP063333:82112-82393 [Escherichia coli]
ATGACCTATGAACTGGCTTTTGACCGTAGAGCACTGAAGGAATGGCAGAAACTCGGCCACACCATCCGTGAACAATTCAA
AAAGAAACTGGCAGAACGGCTGGAAAATCCACGCGTACCCGCAGCCCGGTTACATGGCCATGCTGATCGCTATAAAATCA
AACTTCGTGCATCTGGCTACAGACTTGTATACCAAGTCATTGATGAGAAAGTCGTTTTACTCGTTATTGCCGTTGGAAGA
AGGGAAAGCAGCGAAGTCTATCAGATCGCAGATTTGCGCTAA
ATGACCTATGAACTGGCTTTTGACCGTAGAGCACTGAAGGAATGGCAGAAACTCGGCCACACCATCCGTGAACAATTCAA
AAAGAAACTGGCAGAACGGCTGGAAAATCCACGCGTACCCGCAGCCCGGTTACATGGCCATGCTGATCGCTATAAAATCA
AACTTCGTGCATCTGGCTACAGACTTGTATACCAAGTCATTGATGAGAAAGTCGTTTTACTCGTTATTGCCGTTGGAAGA
AGGGAAAGCAGCGAAGTCTATCAGATCGCAGATTTGCGCTAA
Antitoxin
Download Length: 164 bp
>AT147841 NZ_CP047796:c2166506-2166343 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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