Detailed information of TA system TA147833

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 567955..568152
• Replicon: chromosome
• Accession: NZ_CP047796
• Organism: Staphylococcus aureus strain UP_462

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: E3S78_RS02645
• Protein ID: WP_000623369.1
• Coordinates: 568045..568152 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	567955..567992 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S78_RS02610	563148..563435	-	288	WP_000410718.1	hypothetical protein	-
E3S78_RS02615	563776..564066	+	291	WP_001791476.1	hypothetical protein	-
E3S78_RS02620	564154..564795	-	642	WP_000571191.1	ABC transporter ATP-binding protein	-
E3S78_RS02625	564792..565112	-	321	WP_000873929.1	YxeA family protein	-
E3S78_RS02630	565115..567079	-	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
E3S78_RS02635	567123..567395	-	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
E3S78_RS02640	567405..567506	-	102	WP_001790623.1	hypothetical protein	-
-	567955..567992	+	38	-	-	Antitoxin
E3S78_RS02645	568045..568152	-	108	WP_000623369.1	putative holin-like toxin	Toxin
E3S78_RS02650	568423..569025	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
E3S78_RS02655	569040..569216	-	177	WP_000214898.1	YkvS family protein	-
E3S78_RS02660	569415..570401	+	987	WP_000668820.1	lipoate--protein ligase	-
E3S78_RS02665	570482..570700	-	219	WP_000876825.1	IDEAL domain-containing protein	-
E3S78_RS02670	570910..571479	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T147833 WP_000623369.1 NZ_CP047796:c568152-568045 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T147833 NZ_CP063332:c2738229-2738122 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 38 bp

>AT147833 NZ_CP047796:567955-567992 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin