Detailed information of TA system TA147800

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2648545..2648807
• Replicon: chromosome
• Accession: NZ_CP047793
• Organism: Staphylococcus aureus strain UP_764

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: E3S87_RS12910
• Protein ID: WP_073392962.1
• Coordinates: 2648545..2648649 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	2648644..2648807 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S87_RS12895	2645341..2646123	+	783	WP_000908186.1	ABC transporter ATP-binding protein	-
E3S87_RS12900	2646191..2647048	+	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
E3S87_RS12905	2647707..2647865	-	159	WP_001792784.1	hypothetical protein	-
E3S87_RS12910	2648545..2648649	+	105	WP_073392962.1	hypothetical protein	Toxin
-	2648644..2648807	-	164	-	-	Antitoxin
E3S87_RS12915	2649075..2650721	-	1647	WP_000277741.1	IS1182-like element ISSau3 family transposase	-
E3S87_RS12920	2651009..2652100	-	1092	WP_000495684.1	hypothetical protein	-
E3S87_RS12925	2652366..2653346	-	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
E3S87_RS12930	2653348..2653668	-	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2649075..2650721	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T147800 WP_073392962.1 NZ_CP047793:2648545-2648649 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T147800 NZ_CP063301:c1582536-1582162 [Klebsiella grimontii]
ATGCAAATACAATCCCTGTCCCCTCAAAGGGCGGCCTCGTCACGTCTGTCGTCAGTCGAAAGCTGGCGAAAATTGCTGGA
GTATCTGCTGAAACAACACTACGGTCTGATGATGAACGACACACCGTTTGGCGACGACAGTGTGATCCAGAAGAACATTG
ATGCGGGAATCTCACTGTGTGATGCGGTGAATTTTATCGTGGAAAAGTACGGTCTGGTGCGTACTGACCGTCACGGCTTC
AGTGTGACAGAGCAGTCTCCGTTCATCGACAGCATCGATATGCTCCGCGCCCGGAAGGCTACCGGGCTGATGACCCGCAA
GGGCTATCAAACCGTTACTGACATCACCAGCGGCAGATCCAGAGGAGGGAAATAA

Antitoxin

Nucleotide

• Length: 164 bp

>AT147800 NZ_CP047793:c2648807-2648644 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Structures

Antitoxin