Detailed information of TA system TA147797

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2360198..2360382
• Replicon: chromosome
• Accession: NZ_CP047793
• Organism: Staphylococcus aureus strain UP_764

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: E3S87_RS11415
• Protein ID: WP_000482647.1
• Coordinates: 2360198..2360305 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2360322..2360382 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S87_RS11390	2355560..2356033	+	474	WP_000456496.1	GyrI-like domain-containing protein	-
E3S87_RS11395	2356156..2357367	-	1212	WP_001191919.1	multidrug effflux MFS transporter	-
E3S87_RS11400	2357549..2358208	-	660	WP_000831298.1	membrane protein	-
E3S87_RS11405	2358268..2359410	-	1143	WP_001176855.1	glycerate kinase	-
E3S87_RS11410	2359678..2360064	+	387	WP_000779351.1	flippase GtxA	-
E3S87_RS11415	2360198..2360305	+	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2360322..2360382	-	61	-	-	Antitoxin
E3S87_RS11420	2360953..2362716	+	1764	WP_001064829.1	ABC transporter ATP-binding protein/permease	-
E3S87_RS11425	2362741..2364474	+	1734	WP_000486505.1	ABC transporter ATP-binding protein/permease	-
E3S87_RS11430	2364705..2364872	+	168	Protein_2213	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T147797 WP_000482647.1 NZ_CP047793:2360198-2360305 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T147797 NZ_CP063295:c14266-13916 [Salmonella enterica subsp. enterica serovar Typhimurium]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin

Nucleotide

• Length: 61 bp

>AT147797 NZ_CP047793:c2360382-2360322 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin