Detailed information of TA system TA147792

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1053755..1053952
• Replicon: chromosome
• Accession: NZ_CP047793
• Organism: Staphylococcus aureus strain UP_764

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: E3S87_RS05220
• Protein ID: WP_000623369.1
• Coordinates: 1053845..1053952 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1053755..1053792 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S87_RS05185	1048948..1049235	-	288	WP_000410718.1	hypothetical protein	-
E3S87_RS05190	1049576..1049866	+	291	WP_001791476.1	hypothetical protein	-
E3S87_RS05195	1049954..1050595	-	642	WP_000571191.1	ABC transporter ATP-binding protein	-
E3S87_RS05200	1050592..1050912	-	321	WP_000873929.1	YxeA family protein	-
E3S87_RS05205	1050915..1052879	-	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
E3S87_RS05210	1052923..1053195	-	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
E3S87_RS05215	1053205..1053306	-	102	WP_001790623.1	hypothetical protein	-
-	1053755..1053792	+	38	-	-	Antitoxin
E3S87_RS05220	1053845..1053952	-	108	WP_000623369.1	putative holin-like toxin	Toxin
E3S87_RS05225	1054223..1054825	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
E3S87_RS05230	1054840..1055016	-	177	WP_000214898.1	YkvS family protein	-
E3S87_RS05235	1055215..1056201	+	987	WP_000668820.1	lipoate--protein ligase	-
E3S87_RS05240	1056282..1056500	-	219	WP_000876825.1	IDEAL domain-containing protein	-
E3S87_RS05245	1056710..1057279	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T147792 WP_000623369.1 NZ_CP047793:c1053952-1053845 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T147792 NZ_CP063278:c59461-59150 [Klebsiella pneumoniae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTAAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin

Nucleotide

• Length: 38 bp

>AT147792 NZ_CP047793:1053755-1053792 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin