Detailed information of TA system TA147790

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 177520..177700
• Replicon: chromosome
• Accession: NZ_CP047793
• Organism: Staphylococcus aureus strain UP_764

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3S87_RS01075
• Protein ID: WP_115390996.1
• Coordinates: 177605..177700 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	177520..177577 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S87_RS01050	172933..175353	-	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-
E3S87_RS01055	175878..176320	+	443	Protein_172	DUF1433 domain-containing protein	-
E3S87_RS01060	176320..176763	+	444	WP_000731421.1	DUF1433 domain-containing protein	-
E3S87_RS01065	176763..177206	+	444	WP_001037039.1	DUF1433 domain-containing protein	-
E3S87_RS01070	177381..177482	-	102	WP_001791232.1	hypothetical protein	-
-	177520..177577	+	58	-	-	Antitoxin
E3S87_RS01075	177605..177700	-	96	WP_115390996.1	type I toxin-antitoxin system Fst family toxin	Toxin
E3S87_RS01080	178151..178597	+	447	WP_000747804.1	DUF1433 domain-containing protein	-
E3S87_RS01085	178790..179359	+	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
E3S87_RS01090	179359..180726	+	1368	WP_001093574.1	FRG domain-containing protein	-
E3S87_RS01095	180875..181447	-	573	WP_000414222.1	hypothetical protein	-
E3S87_RS01100	181545..181889	-	345	WP_000627550.1	DUF3969 family protein	-
E3S87_RS01105	181930..182556	-	627	WP_000669038.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hysA	147758..185115	37357

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3536.28 Da
• Isoelectric Point: 10.4449

>T147790 WP_115390996.1 NZ_CP047793:c177700-177605 [Staphylococcus aureus]
VILIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147790 NZ_CP063277:c4892519-4891986 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCTGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT147790 NZ_CP047793:177520-177577 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin