Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1842600..1842817 Replicon chromosome
Accession NZ_CP047792
Organism Staphylococcus aureus strain UP_794

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag E3S88_RS09230 Protein ID WP_001802298.1
Coordinates 1842713..1842817 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 1842600..1842655 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3S88_RS09210 1838671..1839336 - 666 WP_001024099.1 SDR family oxidoreductase -
E3S88_RS09215 1839488..1839808 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
E3S88_RS09220 1839810..1840790 + 981 WP_124779853.1 CDF family zinc efflux transporter CzrB -
E3S88_RS09225 1841056..1842147 + 1092 WP_124779851.1 transcriptional regulator -
- 1842600..1842655 + 56 - - Antitoxin
E3S88_RS09230 1842713..1842817 - 105 WP_001802298.1 hypothetical protein Toxin
E3S88_RS09235 1842978..1843470 - 493 Protein_1768 recombinase family protein -
E3S88_RS09240 1843521..1844027 - 507 Protein_1769 SAP domain-containing protein -
E3S88_RS09245 1845076..1845933 - 858 WP_072512359.1 Cof-type HAD-IIB family hydrolase -
E3S88_RS09250 1846001..1846783 - 783 WP_124779849.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T147780 WP_001802298.1 NZ_CP047792:c1842817-1842713 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T147780 NZ_CP047792:c1842817-1842713 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT147780 NZ_CP047792:1842600-1842655 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References