Detailed information of TA system TA147771

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1492504..1492684
• Replicon: chromosome
• Accession: NZ_CP047792
• Organism: Staphylococcus aureus strain UP_794

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3S88_RS07220
• Protein ID: WP_001801861.1
• Coordinates: 1492504..1492599 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1492627..1492684 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S88_RS07195	1487907..1488533	+	627	WP_124780439.1	hypothetical protein	-
E3S88_RS07200	1488574..1488897	+	324	WP_160194556.1	DUF3969 family protein	-
E3S88_RS07205	1489016..1489588	+	573	WP_124780437.1	hypothetical protein	-
E3S88_RS07210	1489963..1490799	+	837	WP_124780435.1	ABC transporter ATP-binding protein	-
E3S88_RS07215	1491606..1492052	-	447	WP_124780431.1	DUF1433 domain-containing protein	-
E3S88_RS07220	1492504..1492599	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1492627..1492684	-	58	-	-	Antitoxin
E3S88_RS07225	1492722..1492823	+	102	WP_124780429.1	hypothetical protein	-
E3S88_RS07230	1492999..1493340	-	342	Protein_1412	DUF1433 domain-containing protein	-
E3S88_RS07235	1493373..1494940	+	1568	WP_160194503.1	IS3-like element ISSau2 family transposase	-
E3S88_RS07240	1495105..1495548	-	444	WP_124781652.1	DUF1433 domain-containing protein	-
E3S88_RS07245	1495548..1495994	-	447	WP_185648675.1	DUF1433 domain-containing protein	-
E3S88_RS07250	1495994..1496437	-	444	WP_160194557.1	DUF1433 domain-containing protein	-
E3S88_RS07255	1496437..1496879	-	443	Protein_1417	DUF1433 domain-containing protein	-
E3S88_RS07260	1496879..1497322	-	444	WP_160194558.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T147771 WP_001801861.1 NZ_CP047792:1492504-1492599 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147771 NZ_CP063242:3277559-3277978 [Pectobacterium carotovorum]
ATGACAGATATCTTGCTCAACAAAAGCAGCACCATACAAAGATGCCTACGTCGTATTCGTGAGGAATTCGATACTGAGGA
AGGGTTTCGTCAAAACTTCACCAAGCAAGATTCCGTCATACTTAACATACAGCGTGCCTGCGAAGCCTCTATTGATATCG
CTAATTATCTTATCCGTATCAAGCAGCTAGGCATACCACAAAGTAGCCGCGATAGCTTCGCGCTTCTTGCTGCAAACCAG
ATTATTACGATTGATCTGTCTGACAATTTGCAAAAAATGGTGGGATTAAGAAATATTGCCGTGCATGACTATCAGGCGCT
CAATCTGGATATTGTCATCCACGTCATTTCTCATCGTTTAAGCGACTTTGAACATTTTATCAAACAAATAGCCCGGTACA
GCGACAGCCAGCACCTTTAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT147771 NZ_CP047792:c1492684-1492627 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin