Detailed information of TA system TA147764

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1974854..1975070
• Replicon: chromosome
• Accession: NZ_CP047791
• Organism: Staphylococcus aureus strain UP_818

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: E3S89_RS10055
• Protein ID: WP_073392962.1
• Coordinates: 1974966..1975070 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1974854..1974909 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S89_RS10035	1969948..1970268	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
E3S89_RS10040	1970270..1971250	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
E3S89_RS10045	1971516..1972607	+	1092	WP_000495684.1	hypothetical protein	-
E3S89_RS10050	1972895..1974508	+	1614	WP_000277742.1	IS1182-like element ISSau3 family transposase	-
-	1974854..1974909	+	56	-	-	Antitoxin
E3S89_RS10055	1974966..1975070	-	105	WP_073392962.1	hypothetical protein	Toxin
E3S89_RS10060	1975750..1975908	+	159	WP_001792784.1	hypothetical protein	-
E3S89_RS10065	1976567..1977424	-	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
E3S89_RS10070	1977492..1978274	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1972895..1974508	1613

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T147764 WP_073392962.1 NZ_CP047791:c1975070-1974966 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T147764 NZ_CP063241:c3829403-3828987 [Pectobacterium brasiliense]
GTGAGTCTCTTGTTCATGCTGGATACCAATATCTGTTCCTTCATTATGCGGGAACACCCTGCGGAGGTGATTGAAAAGTT
GCAGCAATGCACGCTGCGGCGTGATCGTATTGTGGTCTCTGCCATCACTTACGCTGAAATGCGTTTCGGGGCGGTTGGTA
AAAAAGCCTCGCCACGCCATATGCAACTGGTCGATGCTTTTTGCCGTCGGCTTGATGCGGTATTACCTTGGGATAGCGCC
GCAGTAGATGCCACCACGAAAATCAAAATCGAGCTAGCCGCCGCTGGCACACCTATTGGTCCAAACGATACGGCCATCGC
GGGCCATGCCATCAGCGCTAAGGCCATATTAGTCACCAATAATCTGAGAGAATTTGAGCGAGTACCGGGGCTGACGTTGG
AAGATTGGGTTAAATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT147764 NZ_CP047791:1974854-1974909 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin