Detailed information of TA system TA147755

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1626911..1627091
• Replicon: chromosome
• Accession: NZ_CP047791
• Organism: Staphylococcus aureus strain UP_818

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3S89_RS07995
• Protein ID: WP_001801861.1
• Coordinates: 1626911..1627006 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1627034..1627091 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S89_RS07965	1622055..1622681	+	627	WP_000669038.1	hypothetical protein	-
E3S89_RS07970	1622722..1623066	+	345	WP_000627550.1	DUF3969 family protein	-
E3S89_RS07975	1623164..1623736	+	573	WP_000414222.1	hypothetical protein	-
E3S89_RS07980	1623885..1625252	-	1368	WP_160199026.1	FRG domain-containing protein	-
E3S89_RS07985	1625252..1625821	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
E3S89_RS07990	1626014..1626460	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
E3S89_RS07995	1626911..1627006	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1627034..1627091	-	58	-	-	Antitoxin
E3S89_RS08000	1627129..1627230	+	102	WP_001791232.1	hypothetical protein	-
E3S89_RS08005	1627405..1627848	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
E3S89_RS08010	1627848..1628291	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
E3S89_RS08015	1628291..1628733	-	443	Protein_1573	DUF1433 domain-containing protein	-
E3S89_RS08020	1629258..1631678	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hysA / selk	1619496..1656853	37357

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T147755 WP_001801861.1 NZ_CP047791:1626911-1627006 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147755 NZ_CP063241:c187969-187790 [Pectobacterium brasiliense]
ATGGATAGCAGGACGTTAATAGCAGAAATCAAGGCCGATGGGTGGGAACTGATAAGAGTGAACGGAAGCCACCACCATTT
TATGCATCCTAGTAAACTGGGGTTAGTCACAATCCCCCACCCTAAGAAAGATTTACCGATAGGCACGGTAAAAAGCATCA
GGAAACAAGCAGGAATATGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT147755 NZ_CP047791:c1627091-1627034 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin