Detailed information of TA system TA147738

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 183493..183673
• Replicon: chromosome
• Accession: NZ_CP047790
• Organism: Staphylococcus aureus strain UP_830

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3S90_RS01130
• Protein ID: WP_001801861.1
• Coordinates: 183578..183673 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	183493..183550 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S90_RS01100	179844..180962	+	1119	WP_000072558.1	restriction endonuclease subunit S	-
E3S90_RS01105	181610..182026	+	417	WP_020978241.1	DUF1433 domain-containing protein	-
E3S90_RS01110	182263..182610	+	348	WP_001566695.1	DUF1433 domain-containing protein	-
E3S90_RS01115	182632..183006	+	375	WP_000695818.1	DUF1433 domain-containing protein	-
E3S90_RS01120	183194..183376	+	183	Protein_185	transposase	-
E3S90_RS01125	183354..183455	-	102	WP_001791232.1	hypothetical protein	-
-	183493..183550	+	58	-	-	Antitoxin
E3S90_RS01130	183578..183673	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
E3S90_RS01135	184124..184570	+	447	WP_000747802.1	DUF1433 domain-containing protein	-
E3S90_RS01140	185255..185638	+	384	WP_000070811.1	hypothetical protein	-
E3S90_RS01145	185649..185825	+	177	WP_000375476.1	hypothetical protein	-
E3S90_RS01155	186196..186753	+	558	WP_000864139.1	ImmA/IrrE family metallo-endopeptidase	-
E3S90_RS01160	186951..187523	-	573	WP_000414206.1	hypothetical protein	-
E3S90_RS01165	187624..187965	-	342	WP_000627547.1	DUF3969 family protein	-
E3S90_RS01170	188006..188632	-	627	WP_000669021.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hlgA / lukD	126449..220366	93917

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T147738 WP_001801861.1 NZ_CP047790:c183673-183578 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147738 NZ_CP063233:c5950374-5950030 [Pseudomonas fluorescens]
ATGCGTTCTATTTTCTTCGAGACTTCATCGTTTACCGCCACCGTAGGTCATTACCTGACGGATGATGAATATCGATTGCT
GCAAAACGAGATGCAGTGGAACCCTTTGGCTGGCGATGTGATGCCCCGTACAGGAGGGTTTCGCAAGCTACGGTGGTCAG
ATGGCAAGCGTGGTAAAGGAAAGCGTAGTGGCTTACGGGTTATTTACTACTGGCTCACCACTGATGGTCACTTTTGGATG
TTTGCTATCTACAACAAAGACGAATTGGAAAATTTGACTGCCGATCAAGAGAAGGCACTTAAAAAGGCCATAGAGGCCGA
ACTGAAAAAACGAGGTACCCCATGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT147738 NZ_CP047790:183493-183550 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin