Detailed information of TA system TA147722

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 179101..179283
• Replicon: chromosome
• Accession: NZ_CP047789
• Organism: Staphylococcus aureus strain UP_967

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3S93_RS01085
• Protein ID: WP_001801861.1
• Coordinates: 179188..179283 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	179101..179160 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S93_RS01070	178239..178616	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
E3S93_RS01075	178810..178986	+	177	Protein_176	transposase	-
E3S93_RS01080	178964..179065	-	102	WP_001791893.1	hypothetical protein	-
-	179101..179160	+	60	-	-	Antitoxin
E3S93_RS01085	179188..179283	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
E3S93_RS01090	179486..179629	+	144	WP_001549059.1	transposase	-
E3S93_RS01095	180233..180616	+	384	WP_000070811.1	hypothetical protein	-
E3S93_RS01100	180627..180803	+	177	WP_000375476.1	hypothetical protein	-
E3S93_RS01105	180805..180990	+	186	WP_000809857.1	hypothetical protein	-
E3S93_RS01110	181104..181745	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
E3S93_RS01115	181963..182514	-	552	WP_000414205.1	hypothetical protein	-
E3S93_RS01120	182612..182956	-	345	WP_000627551.1	DUF3969 family protein	-
E3S93_RS01125	182997..183623	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	146012..205321	59309

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T147722 WP_001801861.1 NZ_CP047789:c179283-179188 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147722 NZ_CP063229:c1154143-1153940 [Serratia marcescens]
ATGACTAAAACCGACTATCTGATGCGTTTACGTAAATGCACCACGATTGATACTCTCGAACGTGTTATTGAGAAAAATAA
GTACGAGCTTTCCGATGATGAACTGGAGCTGTTTTACTCAGCGGCCGATCACCGTCTGGCGGAGCTCACCATGAACAAAC
TGTATGACAAAATCCCCACCGCCGTTTGGAAATATGTCAGGTAA

Antitoxin

Nucleotide

• Length: 60 bp

>AT147722 NZ_CP047789:179101-179160 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin