Detailed information of TA system TA147712

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2675720..2675998
• Replicon: chromosome
• Accession: NZ_CP047788
• Organism: Staphylococcus aureus strain UP_1033

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: E3S95_RS13115
• Protein ID: WP_073392962.1
• Coordinates: 2675720..2675824 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2675820..2675998 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S95_RS13100	2672516..2673298	+	783	WP_000908186.1	ABC transporter ATP-binding protein	-
E3S95_RS13105	2673366..2674223	+	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
E3S95_RS13110	2674882..2675040	-	159	WP_001792784.1	hypothetical protein	-
E3S95_RS13115	2675720..2675824	+	105	WP_073392962.1	hypothetical protein	Toxin
-	2675820..2675998	-	179	-	-	Antitoxin
E3S95_RS13120	2676250..2677896	-	1647	WP_000277741.1	IS1182-like element ISSau3 family transposase	-
E3S95_RS13125	2678184..2679275	-	1092	WP_160193961.1	transcriptional regulator	-
E3S95_RS13130	2679541..2680521	-	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
E3S95_RS13135	2680523..2680843	-	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2676250..2677896	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T147712 WP_073392962.1 NZ_CP047788:2675720-2675824 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T147712 NZ_CP063224:c297205-296903 [Enterobacter hormaechei subsp. steigerwaltii]
ATCAAGGAGATCGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAATTTAAAGGACAGGCGGGCAAAGACGATTATCGC
CTCCCGCCTCTTTAGGCTGGCAAATGGCTTAGCGGGCGACATTAGACCTGTGGGAGAAGGTATCAGTGAACTGAGGATCC
ACTTTGGCCCGGGCTACAGGATCTATTTTAAGGACCAGGGCAATTGCATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Antitoxin

Nucleotide

• Length: 179 bp

>AT147712 NZ_CP047788:c2675998-2675820 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Structures

Antitoxin