Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2385600..2385784 Replicon chromosome
Accession NZ_CP047788
Organism Staphylococcus aureus strain UP_1033

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag E3S95_RS11615 Protein ID WP_000482647.1
Coordinates 2385600..2385707 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2385724..2385784 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3S95_RS11590 2380962..2381435 + 474 WP_000456496.1 GyrI-like domain-containing protein -
E3S95_RS11595 2381558..2382769 - 1212 WP_001191919.1 multidrug effflux MFS transporter -
E3S95_RS11600 2382951..2383610 - 660 WP_000831298.1 membrane protein -
E3S95_RS11605 2383670..2384812 - 1143 WP_001176855.1 glycerate kinase -
E3S95_RS11610 2385080..2385466 + 387 WP_000779351.1 flippase GtxA -
E3S95_RS11615 2385600..2385707 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2385724..2385784 - 61 - - Antitoxin
E3S95_RS11620 2386355..2388118 + 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
E3S95_RS11625 2388143..2389876 + 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
E3S95_RS11630 2390107..2390274 + 168 Protein_2257 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T147708 WP_000482647.1 NZ_CP047788:2385600-2385707 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T147708 NZ_CP063216:c92049-91624 [Klebsiella pneumoniae]
ATGAAGAAAACCTGGATGCTCGACACTAACATCTGCTCGTTCATCATGCGCGAGCAGCCGGCAGCGGTGCTGAAGCGCCT
GGAGCAGGTGGTGCTGCGCGGTGATCGCATCGTGGTCTCGGCCGTGACGTATGCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAAGCCTCGCCGCGCCATATTCAGCTGGTCGACGCGTTCTGCGCGCGCCTCGATGCCATCCTGCCCTGGGACCGGGCT
GCGGTGGACGCCACGACGGACATCCGGGTGGCGCTGCGCCTCGCCGGGACGCCGATCGGCCCGAACGACACCGCCATTGC
CGGACACGCCATCGCGGCGGGCGCCATCCTGGTGACGAATAATACAAGAGAGTTTGAGCGGGTGCCGGGTCTGGTTCTGG
AAGACTGGGTTGGCTTTGTTGAATAA

Antitoxin


Download         Length: 61 bp

>AT147708 NZ_CP047788:c2385784-2385724 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7


Antitoxin

Download structure file

References