Detailed information of TA system TA147698

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 177592..177772
• Replicon: chromosome
• Accession: NZ_CP047788
• Organism: Staphylococcus aureus strain UP_1033

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3S95_RS01075
• Protein ID: WP_001801861.1
• Coordinates: 177677..177772 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	177592..177649 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3S95_RS01050	173005..175425	-	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-
E3S95_RS01055	175950..176392	+	443	Protein_173	DUF1433 domain-containing protein	-
E3S95_RS01060	176392..176835	+	444	WP_000731421.1	DUF1433 domain-containing protein	-
E3S95_RS01065	176835..177278	+	444	WP_001037039.1	DUF1433 domain-containing protein	-
E3S95_RS01070	177453..177554	-	102	WP_001791232.1	hypothetical protein	-
-	177592..177649	+	58	-	-	Antitoxin
E3S95_RS01075	177677..177772	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
E3S95_RS01080	178223..178669	+	447	WP_000747804.1	DUF1433 domain-containing protein	-
E3S95_RS01085	178862..179431	+	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
E3S95_RS01090	179431..180798	+	1368	WP_001093574.1	FRG domain-containing protein	-
E3S95_RS01095	180947..181519	-	573	WP_000414222.1	hypothetical protein	-
E3S95_RS01100	181617..181961	-	345	WP_000627550.1	DUF3969 family protein	-
E3S95_RS01105	182002..182628	-	627	WP_000669038.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hysA	147830..185187	37357

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T147698 WP_001801861.1 NZ_CP047788:c177772-177677 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147698 NZ_CP063215:1881096-1881198 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin

Nucleotide

• Length: 58 bp

>AT147698 NZ_CP047788:177592-177649 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin