Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2620387..2620650 Replicon chromosome
Accession NZ_CP047786
Organism Staphylococcus aureus strain UP_1150

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag E3S98_RS12815 Protein ID WP_001802298.1
Coordinates 2620387..2620491 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2620486..2620650 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3S98_RS12790 2615772..2616554 + 783 WP_000908177.1 ABC transporter ATP-binding protein -
E3S98_RS12795 2616622..2617479 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
E3S98_RS12800 2618174..2618275 - 102 WP_045173434.1 hypothetical protein -
E3S98_RS12805 2618564..2619700 + 1137 WP_000115564.1 SAP domain-containing protein -
E3S98_RS12810 2619743..2620226 + 484 Protein_2473 recombinase family protein -
E3S98_RS12815 2620387..2620491 + 105 WP_001802298.1 hypothetical protein Toxin
- 2620486..2620650 - 165 - - Antitoxin
E3S98_RS12820 2620934..2622025 - 1092 WP_000495671.1 lytic regulatory protein -
E3S98_RS12825 2622291..2623271 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
E3S98_RS12830 2623273..2623593 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
E3S98_RS12835 2623745..2624410 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T147679 WP_001802298.1 NZ_CP047786:2620387-2620491 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T147679 NZ_CP063214:c1043384-1043282 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 165 bp

>AT147679 NZ_CP047786:c2620650-2620486 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References