Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2335873..2336057 Replicon chromosome
Accession NZ_CP047786
Organism Staphylococcus aureus strain UP_1150

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag E3S98_RS11325 Protein ID WP_000482647.1
Coordinates 2335873..2335980 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2335997..2336057 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3S98_RS11300 2331235..2331708 + 474 WP_160191674.1 GyrI-like domain-containing protein -
E3S98_RS11305 2331831..2333042 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
E3S98_RS11310 2333224..2333883 - 660 WP_000831298.1 membrane protein -
E3S98_RS11315 2333943..2335085 - 1143 WP_001176863.1 glycerate kinase -
E3S98_RS11320 2335353..2335739 + 387 WP_000779360.1 flippase GtxA -
E3S98_RS11325 2335873..2335980 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2335997..2336057 - 61 - - Antitoxin
E3S98_RS11330 2336628..2338391 + 1764 WP_045172654.1 ABC transporter ATP-binding protein/permease -
E3S98_RS11335 2338416..2340149 + 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
E3S98_RS11340 2340380..2340547 + 168 WP_001790576.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T147676 WP_000482647.1 NZ_CP047786:2335873-2335980 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T147676 NZ_CP063214:c528544-528350 [Escherichia coli]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA

Antitoxin


Download         Length: 61 bp

>AT147676 NZ_CP047786:c2336057-2335997 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References