Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2093071..2093268 Replicon chromosome
Accession NZ_CP047784
Organism Staphylococcus aureus strain UP_1209

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag E3T00_RS10225 Protein ID WP_001802298.1
Coordinates 2093164..2093268 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2093071..2093109 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3T00_RS10205 2089189..2089854 - 666 WP_001024095.1 SDR family oxidoreductase -
E3T00_RS10210 2090006..2090326 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
E3T00_RS10215 2090328..2091308 + 981 WP_043044038.1 CDF family zinc efflux transporter CzrB -
E3T00_RS10220 2091574..2092665 + 1092 WP_000495682.1 hypothetical protein -
- 2093071..2093109 + 39 - - Antitoxin
E3T00_RS10225 2093164..2093268 - 105 WP_001802298.1 hypothetical protein Toxin
E3T00_RS10230 2093948..2094106 + 159 WP_001792784.1 hypothetical protein -
E3T00_RS10235 2094764..2095621 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
E3T00_RS10240 2095689..2096471 - 783 WP_043044040.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T147654 WP_001802298.1 NZ_CP047784:c2093268-2093164 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T147654 NZ_CP063167:1288693-1288989 [Variovorax paradoxus]
ATGCCACAAGTGAGGTTCACGCCTGCGGCGCTGCGCGACTTGCAGCGTTTGCGTGAGTTCTTGCGTCCAAAAAACCCGCA
AGCAGCGCGGCGCGCTGCTCTAAGTATTTTGCAGGGCGTGAAGGTGCTGGGTTTGCAGCCGTTGATCGGACGGCCGCTGG
AGGATTTGCCCCCTGAGTATCGCGAGTGGGTGATCGACTTCGGTAGCGGCGGTTACGTATCGCTTTACCGGTACGACGAA
GACATCGATGTGGTCACGGTGCTGGCTCTGCGTCATCAGCGCGAGGCCGGCTACTGA

Antitoxin


Download         Length: 39 bp

>AT147654 NZ_CP047784:2093071-2093109 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References