Detailed information of TA system TA147648

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1809163..1809343
• Replicon: chromosome
• Accession: NZ_CP047784
• Organism: Staphylococcus aureus strain UP_1209

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: E3T00_RS08625
• Protein ID: WP_001801861.1
• Coordinates: 1809163..1809258 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1809286..1809343 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T00_RS08595	1804253..1804903	+	651	WP_072490651.1	excalibur calcium-binding domain-containing protein	-
E3T00_RS08600	1804984..1805979	+	996	WP_043044072.1	DUF4352 domain-containing protein	-
E3T00_RS08605	1806054..1806680	+	627	WP_043044073.1	hypothetical protein	-
E3T00_RS08610	1806721..1807062	+	342	WP_000627540.1	DUF3969 family protein	-
E3T00_RS08615	1807163..1807735	+	573	WP_023914802.1	hypothetical protein	-
E3T00_RS08625	1809163..1809258	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1809286..1809343	-	58	-	-	Antitoxin
E3T00_RS08630	1809381..1809482	+	102	WP_001791232.1	hypothetical protein	-
E3T00_RS08635	1809658..1810100	-	443	Protein_1687	DUF1433 domain-containing protein	-
E3T00_RS08640	1810100..1810543	-	444	WP_043044078.1	DUF1433 domain-containing protein	-
E3T00_RS08645	1810543..1810986	-	444	WP_043044079.1	DUF1433 domain-containing protein	-
E3T00_RS08650	1810986..1811429	-	444	WP_000747799.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T147648 WP_001801861.1 NZ_CP047784:1809163-1809258 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T147648 NZ_CP063164:1509552-1509845 [Sulfurovum indicum]
ATGAATAAAGAATTGATCCCTTTTGATCTAGTAGAATATTTGGACAATGAAGAAGCAATGGCAGAATATCTTTCCCAAGT
ACTCGAAGATGGAGATAATGATGAGTTTCTAAGAGCTATAGGGTATCTCGCCAAAGCCAAAGGCATGGCGCAAATTGCCA
AAGAGACAGGCATGGGGAGAGAAAGCCTATATAAGGCGTTTCGTCCCAACGCCAAGCCACGCTTTGATACAGTCATGAAA
GTACTTCATGCTTTGAAGCTCCAGTTGACAGCAGCACCACAGTTGCATCAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT147648 NZ_CP047784:c1809343-1809286 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin