Detailed information of TA system TA147631

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprG3-SprA2AS/-
• Location: 1981893..1982155
• Replicon: chromosome
• Accession: NZ_CP047782
• Organism: Staphylococcus aureus strain UP_1352

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: E3T04_RS10110
• Protein ID: WP_073392962.1
• Coordinates: 1982051..1982155 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1981893..1982056 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
E3T04_RS10090	1977032..1977352	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
E3T04_RS10095	1977354..1978334	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
E3T04_RS10100	1978600..1979691	+	1092	WP_000495684.1	hypothetical protein	-
E3T04_RS10105	1979979..1981625	+	1647	WP_000277741.1	IS1182-like element ISSau3 family transposase	-
-	1981893..1982056	+	164	-	-	Antitoxin
E3T04_RS10110	1982051..1982155	-	105	WP_073392962.1	hypothetical protein	Toxin
E3T04_RS10115	1982835..1982993	+	159	WP_001792784.1	hypothetical protein	-
E3T04_RS10120	1983652..1984509	-	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
E3T04_RS10125	1984577..1985359	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1979979..1981625	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T147631 WP_073392962.1 NZ_CP047782:c1982155-1982051 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T147631 NZ_CP063153:c3958247-3957933 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAATCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTCGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCCGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin

Nucleotide

• Length: 164 bp

>AT147631 NZ_CP047782:1981893-1982056 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Structures

Antitoxin